Low-Cost Active Thermography using Cellphone Infrared Cameras: from Early Detection of Dental Caries to Quantification of THC in Oral Fluid
Low-Cost Active Thermography using Cellphone Infrared Cameras: from Early Detection of Dental Caries to Quantification of THC in Oral Fluid
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DOI：
10.1038/s41598-020-64796-6
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发表时间：
2020-05-12
影响因子：
4.6
通讯作者：
Tabatabaei, Nima
中科院分区：
文献类型：
--
作者：
Samadi, Nakisa;Thapa, Damber;Tabatabaei, Nima
主动热成像（AT）是一种广泛研究的非破坏性测试方法，用于生物和工业材料的表征和评估。尽管AT具有广泛的潜在应用，但其商业化和广泛适应长期以来一直受到红外（IR）相机的成本和尺寸的阻碍。在本文中，我们证明，这种成本和尺寸的限制，可以克服使用手机附件红外相机。开发了一个软件开发工具包（SDK），通过简单的USB接口控制相机属性，并以高达33 fps的恒定帧速率获取相机帧。为了证明我们的低成本AT系统的性能，我们报告和讨论我们的实验结果对两个高影响的潜在应用。第一组实验是在牙齿样本上进行的，以研究所开发的用于检测早期龋齿的低成本技术的临床潜力，而第二组实验是在基于口腔流体的侧流免疫测定法上进行的，以确定我们的技术用于检测和量化在护理点的大麻消费的可行性。我们的研究结果表明，在低成本的平台上实现可靠的性能，可与昂贵和庞大的研究级系统相媲美，为AT技术向市场的转化铺平了道路。
Active thermography (AT) is a widely studied non-destructive testing method for the characterization and evaluation of biological and industrial materials. Despite its broad range of potential applications, commercialization and wide-spread adaption of AT has long been impeded by the cost and size of infrared (IR) cameras. In this paper, we demonstrate that this cost and size limitation can be overcome using cell-phone attachment IR cameras. A software development kit (SDK) is developed that controls camera attributes through a simple USB interface and acquires camera frames at a constant frame rate up to 33 fps. To demonstrate the performance of our low-cost AT system, we report and discuss our experimental results on two high impact potential applications. The first set of experiments is conducted on a dental sample to investigate the clinical potential of the developed low-cost technology for detecting early dental caries, while the second set of experiments is conducted on the oral-fluid based lateral flow immunoassay to determine the viability of our technology for detecting and quantifying cannabis consumption at the point-of-care. Our results suggest achievement of reliable performance in the low-cost platform, comparable to those of costly and bulky research-grade systems, paving the way for translation of AT techniques to market.