EFFECTS OF CHANGING HYPOTHALAMIC TEMPERATURE ON ECCRINE SWEATING IN THE PATAS MONKEY
EFFECTS OF CHANGING HYPOTHALAMIC TEMPERATURE ON ECCRINE SWEATING IN THE PATAS MONKEY
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DOI：
10.1016/0361-9230(88)90176-1
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发表时间：
1988-02-01
影响因子：
3.8
通讯作者：
KREGEL, KC
中科院分区：
文献类型：
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作者：
GISOLFI, CV;OWEN, MD;KREGEL, KC
在两只雄性（10-13 kg）红猴（Erythrocebus patas）体内植入双侧热电棒以控制下丘脑温度。将动物限制在灵长类动物椅子上，并使用仪器测量下丘脑（THYPO）、结肠（Tc）和平均皮肤（.hivin.Tsk）温度、胸部出汗率（.ovrhdot.msw）和心率（HR）。使用插入非灌注热电极尖端的热电偶监测THYPO;使用电阻湿度计测量MSW。在猴平衡至选定的环境温度后，用温控浴中的水灌注4个恒温器。将THYPO从37度增加到41度。C使MSW从0.05增加到0.30 mg. cm-2.cntdot. min-1。降低hivin.Tsk使THYPO：.ovrhdot.msw关系向右移动（p < 0.05），而没有显著改变其斜率。活动引起的变化，在HR，THYPO是恒定的，引起波动正在进行的出汗，密切跟踪HR. We的结论是，.ovrhdot.MSW在patas猴是由外周和中央的热输入和非热因素。
Two male (10-13 kg) patas monkeys (Erythrocebus patas) were implanted with bilateral thermodes to control hypothalamic temperature. Animals were restrained in primate chairs and instrumented to yield hypothalamic (THYPO), colonic (Tc), and mean skin (.hivin.Tsk) temperatures, chest sweat rate (.ovrhdot.msw), and heart rate (HR). THYPO was monitored using a thermocouple inserted to the tip of a non-perfused thermode; .ovrhdot.msw was measured using resistance hygrometry. After the monkey euqilibrated to a selected ambient temperature, four thermodes were perfused with water from a temperature-controlled bath. Increasing THYPO from 37 to 41.degree. C increased .ovrhdot.msw from 0.05 to 0.30 mg .cntdot. cm-2 .cntdot. min-1. Reducing .hivin.Tsk shifted the THYPO:.ovrhdot.msw relationship to the right (p < 0.05) without significantly altering its slope. Activity-induced changes in HR, when THYPO was constant, caused fluctuations in ongoing sweating that closely tracked HR. We conclude that .ovrhdot.msw in the patas monkey is controlled by both peripheral and central thermal inputs and nonthermal factors.