Effects of age on navigation strategy.
Effects of age on navigation strategy.
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DOI：
10.1016/j.neurobiolaging.2010.07.021
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发表时间：
2012-01
影响因子：
4.2
通讯作者：
Moffat SD
中科院分区：
文献类型：
--
作者：
Rodgers MK;Sindone JA 3rd;Moffat SD
导航策略的年龄差异已在动物中得到证实，老年动物更倾向于自我中心（路线）策略，而年轻动物更倾向于非自我中心（地点）策略。使用一种新的虚拟Y-迷宫策略评估（vYSA），本研究表明，在人类的策略偏好有很大的年龄差异。老年人压倒性地倾向于自我中心的策略，而年轻人平均分布在自我中心和非自我中心的偏好之间。在Y-迷宫策略评估中，对allocentric策略的偏好仅在年轻人中被发现有利于独立评估（虚拟Morris水任务）的表现。这些结果建立了空间策略的基线年龄差异，并表明这可能会影响其他空间导航评估的表现。在海马结构和功能的年龄差异的框架内解释的结果。
Age differences in navigation strategies have been demonstrated in animals, with aged animals more likely to prefer an egocentric (route) strategy and younger animals more likely to prefer an allocentric (place) strategy. Using a novel virtual Y-maze strategy assessment (vYSA), the present study demonstrated substantial age differences in strategy preference in humans. Older adults overwhelmingly preferred an egocentric strategy, while younger adults were equally distributed between egocentric and allocentric preference. A preference for allocentric strategy on the Y-maze strategy assessment was found to benefit performance on an independent assessment (virtual Morris water task) only in younger adults. These results establish baseline age differences in spatial strategies and suggest this may impact performance on other spatial navigation assessments. The results are interpreted within the framework of age differences in hippocampal structure and function.