QUANTITATIVE NUCLEAR IMAGE ANALYSIS - DIFFERENTIATION BETWEEN NORMAL, HYPERPLASTIC, AND MALIGNANT APPEARING UTERINE GLANDS IN A PARAFFIN SECTION .2. COMPUTER-ASSISTED RECOGNITION BY DISCRIMINANT-ANALYSIS
QUANTITATIVE NUCLEAR IMAGE ANALYSIS - DIFFERENTIATION BETWEEN NORMAL, HYPERPLASTIC, AND MALIGNANT APPEARING UTERINE GLANDS IN A PARAFFIN SECTION .2. COMPUTER-ASSISTED RECOGNITION BY DISCRIMINANT-ANALYSIS
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DOI：
10.1016/0028-2243(77)90069-7
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发表时间：
1977-01-01
影响因子：
2.6
通讯作者：
BAAK, JPA
中科院分区：
文献类型：
--
作者：
DIEGENBACH, PC;BAAK, JPA
定量图像分析应用于石蜡切片中细胞核[来自人子宫腺]的显微镜光度测定数据。对形态正常、不典型增生和癌变子宫腺细胞核的测量结果进行判别分析。用这种方法可以区分3组原子核。根据所使用的变量的（子）集，所有细胞核的60-70%被正确分类为3组中的1组。其中1组对其他2组的歧视导致高达81%的正确分类。判别分析提供了以客观的方式辅助诊断的可能性。
Quantitative image analysis was applied to data from microscope photometry of nuclei [from human uterine glands] in a paraffin section. The results from measurements on the nuclei of morphologically normal, atypical hyperplastic and carcinomatous uterine glands were used in discriminant analysis. With this method it is possible to discriminate between the 3 groups of nuclei. Depending on the (sub)set of the variables used, 60-70% of all nuclei are correctly classified in 1 of the 3 groups. Discrimination of 1 of the groups against the other 2 resulted in up to 81% correct classifications. Discriminant analysis offers a possibility of assisting diagnosis in an objective way.