The basement membrane exfoliation syndrome.
The basement membrane exfoliation syndrome.
复制标题
基底膜剥脱综合征。
DOI：
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发表时间：
1979
期刊：
影响因子：
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通讯作者：
B. S. Fine
中科院分区：
文献类型：
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作者：
R. Eagle;R. L. Font;B. S. Fine
此前的观察表明，“晶状体囊假性剥脱”可能是一种细胞产生异常基底膜物质的疾病。电子显微镜研究表明，整个眼前节的细胞可以产生剥脱性物质。该报告描述了睫状体和虹膜上皮细胞上有丰富的脱落物质，但晶状体表面上没有，其上皮细胞完全坏死。在靠近新形成的异常内皮基底膜的前虹膜基质中也观察到剥脱物质，这表明剥脱物质可能是在虹膜内局部产生的。此外，眼眶中短后睫状动脉壁中的典型剥脱材料（最好认为是周期性为 500A 的丝状带状基底膜）表明剥脱过程不仅限于眼组织。术语“基底膜剥脱综合征”是针对该实体提出的。
Previous observations suggest that "pseudoexfoliation of the lens capsule" may be a disease in which cells produce abnormal basement membrane material. Electron microscopic studies indicate that exfoliative material can be produced by cells throughout the anterior segment of the eye. This report describes abundant exfoliative material on the ciliary and iridic epithelia but not on the surface of the lens whose epithelial cells were completely necrotic. Exfoliative material also was observed in the anterior iridic stroma close to a newly formed abnormal endothelial basement membrane, suggesting that exfoliative material may be produced locally within the iris. Furthermore, typical exfoliative material, best considered a filamentous, banded basement membrane with 500-A periodicity, in the wall of a short posterior ciliary artery in the orbit indicates that the exfoliative process is not solely limited to ocular tissues. The term "basement membrane exfoliation syndrome" is proposed for this entity.