On the plasmalogenation of myocardial choline glycerophospholipid during maturation of various vertebrates.
On the plasmalogenation of myocardial choline glycerophospholipid during maturation of various vertebrates.
复制标题
关于各种脊椎动物成熟过程中心肌胆碱甘油磷脂的缩醛磷脂。
DOI：
10.1016/0305-0491(88)90270-2
复制
发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Helmy,FM
中科院分区：
文献类型：
--
作者：
Hack,MH;Helmy,FM
1.通过各种TLC分析获得了从鱼类到哺乳动物的一系列心脏的缩醛磷脂谱。2.所有标本（心室）均含有乙醇胺缩醛磷脂和一些胆碱缩醛磷脂。3.这两种缩醛磷脂的分布部分与（a）胚胎发育和（B）个体发育有关。4.但也有例外。5.胆碱缩醛磷脂的出现之前，其烷酰基前体，表明缩醛磷脂的碱特异性δ 1-烷基去饱和酶。6.从这些数据中，我们提出了一些问题，作为心肌线粒体膜的居住者的缩醛磷脂和前体所发挥的代谢作用。
1. The plasmalogen profiles of a series of hearts from fish to mammals were obtained by various TLC analyses. 2. All specimens (ventricular) contained ethanolamine plasmalogen and some choline plasmalogen, as well. 3. The distribution of these two plasmalogen species was relatable, in part, to (a) phylogeny and (b) ontogeny. 4. There were exceptions. 5. The appearance of choline plasmalogen was preceded by its alkylacyl precursor, suggesting plasmalogenation by a base-specific delta 1-alkyl desaturase. 6. From the data, we have raised some questions as to the metabolic role played by the plasmalogens and precursors as occupants of myocardial mitchondrial membranes.