Whole of population-based cohort study of recovery time from COVID-19 in New South Wales Australia.
Whole of population-based cohort study of recovery time from COVID-19 in New South Wales Australia.
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DOI：
10.1016/j.lanwpc.2021.100193
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发表时间：
2021-07
期刊：
影响因子：
--
通讯作者：
Spokes P
中科院分区：
文献类型：
--
作者：
Liu B;Jayasundara D;Pye V;Dobbins T;Dore GJ;Matthews G;Kaldor J;Spokes P
新冠肺炎会导致持续的症状，但几乎没有系统地收集数据来估计感染后的恢复时间。我们跟踪了2020年1月至5月期间澳大利亚新南威尔士州确诊的94%的新冠肺炎病例，使用每周3-4次电话访谈并链接到住院和死亡数据，以根据症状解决确定他们是否已从新冠肺炎康复。使用具有竞争风险的比例风险模型来估计根据年龄和性别调整后的恢复时间。在分析中，2904例患者获得了康复(中位随访时间16天，范围1-122，智商11-24)。报告症状缓解的2,572例(88.6%)(262/2,572例同时住院)，224(7.8%)例(28/224同时住院)，51(1.8%)例(1.8%)死于新冠肺炎，57(2.0%)例住院但未记录康复日期。其中10天恢复20%，20天恢复60%，30天恢复80%，60天恢复91%，90天恢复93%，120天恢复96%。与30~49岁组相比，0~29岁组恢复的可能性较大(AHR为1.22，95%CI为1.10~1.34)，而50~69岁和70岁以上组恢复的可能性较小(AHR分别为0.74，95%CI为0.67~0.81和0.63，95%CI为0.56~0.71)。男性恢复快于女性(AHR 1.20，95%CI 1.11~1.29)，有并存病史者恢复时间长于无合并症者(AHR 0.90，95%CI 0.83~0.98)。在大多数新冠肺炎病例得到确诊和随访的情况下，80%的新冠肺炎患者在一个月内康复，但约5%的患者在3个月后仍会继续出现症状。新南威尔士州卫生应急优先研究项目
COVID-19 results in persisting symptoms but there is little systematically collected data estimating recovery time following infection. We followed 94% of all COVID-19 cases diagnosed in the Australian state of New South Wales between January and May 2020 using 3-4 weekly telephone interviews and linkage to hospitalisation and death data to determine if they had recovered from COVID-19 based on symptom resolution. Proportional hazards models with competing risks were used to estimate time to recovery adjusted for age and gender. In analyses 2904 cases were followed for recovery (median follow-up time 16 days, range 1-122, IQR 11-24).There were 2572 (88.6%) who reported resolution of symptoms (262/2572 were also hospitalised), 224 (7.8%) had not recovered at last contact (28/224 were also hospitalised), 51 (1.8%) died of COVID-19, and 57 (2.0%) were hospitalised without a documented recovery date. Of those followed, 20% recovered by 10 days, 60% at 20, 80% at 30, 91% at 60, 93% at 90 and 96% at 120 days. Compared to those aged 30-49 years, those 0-29 years were more likely to recover (aHR 1.22, 95%CI 1.10-1.34) while those aged 50-69 and 70+ years were less likely to recover (aHR respectively 0.74, 95%CI 0.67-0.81 and 0.63, 95%CI 0.56-0.71). Men were faster to recover than women (aHR 1.20, 95%CI 1.11-1.29) and those with pre-existing co-morbidities took longer to recover than those without (aHR 0.90, 95%CI 0.83-0.98). In a setting where most cases of COVID-19 were ascertained and followed, 80% of those with COVID-19 recover within a month, but about 5% will continue to experience symptoms 3 months later. NSW Health Emergency Response Priority Research Projects
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影响因子：
24
作者：
Puntmann, Valentina O.;Carerj, M. Ludovica;Nagel, Eike
通讯作者：
Nagel, Eike
影响因子：
16.6
作者：
Griffith GJ;Morris TT;Tudball MJ;Herbert A;Mancano G;Pike L;Sharp GC;Sterne J;Palmer TM;Davey Smith G;Tilling K;Zuccolo L;Davies NM;Hemani G
通讯作者：
Hemani G
DOI：
10.1016/s0140-6736(20)32705-7
发表时间：
2021-02-06
期刊：
Lancet (London, England)
影响因子：
--
作者：
Gorna R;MacDermott N;Rayner C;O'Hara M;Evans S;Agyen L;Nutland W;Rogers N;Hastie C
通讯作者：
Hastie C
影响因子：
168.9
作者：
White, PD;Thomas, JM;Clare, AW
通讯作者：
Clare, AW
影响因子：
3.7
作者：
Fine, JP;Gray, RJ
通讯作者：
Gray, RJ