Clinicopathologic Features of Polypoid Lesions of the Gallbladder and Risk Factors of Gallbladder Cancer

Clinicopathologic Features of Polypoid Lesions of the Gallbladder and Risk Factors of Gallbladder Cancer
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DOI:
10.3346/jkms.2009.24.3.481
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发表时间:
2009-06-01
影响因子:
4.5
通讯作者:
Kim, Sun-Whe
Kim, Sun-Whe
中科院分区:
医学4区
文献类型:
--
作者:
Kwon, Wooil;Jang, Jin-Young;Kim, Sun-Whe

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胆囊息肉样病变(PLG)的良恶性鉴别仅靠影像学检查是困难的。因此,比较良、恶性息肉的临床病理特征,试图找出恶性息肉病变的危险因素。回顾性分析291例经胆囊切除术确诊为PLG的患者的病历,分析年龄、性别、症状、相关胆结石、PLG形态、PLG大小、PLG数目及术前肿瘤标志物。良性PLG 256例(88.0%),恶性PLG 35例(12.0%)。与良性组比较,恶性组年龄大(61.1岁比47.1岁,P
It is difficult to differentiate benign and malignancy in polypoid lesions of the gallbladder (PLG) by solely depending on imaging studies. Therefore clinicopathologic features of benign and malignant polyps are compared in an attempt to identify the risk factors of malignant polypoid lesions. The medical records of 291 patients who were confirmed to have PLG through cholecystectomy were reviewed and analyzed for age, sex, symptom, associated gallstone, morphology of PLG, size of PLG, number of PLG, and preoperative tumor markers. Benign PLG was found in 256 patients (88.0%) and malignant PLG in 35 patients (12.0%). Compared with benign group, the malignant group were older (61.1 yr vs. 47.1 yr, P