The relationship between sleep bruxism behavior and salivary stress biomarker level.
The relationship between sleep bruxism behavior and salivary stress biomarker level.
复制标题
睡眠磨牙行为与唾液压力生物标志物水平之间的关系。
DOI：
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发表时间：
2009
期刊：
影响因子：
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通讯作者：
R. Hosokawa
中科院分区：
文献类型：
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作者：
M. Makino;C. Masaki;Kei Tomoeda;Elyes Kharouf;T. Nakamoto;R. Hosokawa
目的
磨牙症和功能异常是种植体和口腔修复治疗失败的潜在危险因素。然而，磨牙症的病因仍不清楚。本研究试图阐明磨牙症行为和唾液应激生物标志物水平之间的关系。
材料和方法
46名志愿者（23名男性，23名女性）参与了本研究。磨牙症行为的评估使用自填问卷，研究铸件，和BiteStrip，一个微型电子筛选器用于检测睡眠磨牙症。问卷包括六个项目，询问磨牙症，咬合，下颌功能限制和牙列。咬合面磨损从牙模中评估，并计算为上颌牙弓段中的小平面的总和。参与者在家中使用BiteStrip一晚，并评估评分。从参与者中收集两分钟的刺激全唾液样本，以测量嗜铬粒蛋白A（CgA）的日间水平，这是一种主要的唾液应激生物标志物。使用斯皮尔曼R和Kendall tau统计相关性检验对变量之间的关系进行非参数检验。
结果
自报磨牙症与自报颌骨功能受限之间存在正相关。咬合磨损与咬合、颌功能限制或牙列无显著相关性，但与自我报告的磨牙症行为以及BiteStrip评分显著相关。有趣的是，发现CgA水平与BiteStrip评分呈显著负相关。
结论
睡眠磨牙症被认为是一种与压力有关的睡眠障碍。结果表明，白天心理应激水平与夜磨牙行为呈显著负相关。
PURPOSE
Bruxism and parafunctions are potential risk factors for implant and prosthodontic treatment failure. However, the etiology of bruxism remains unknown. This study sought to clarify the relationship between bruxism behavior and a salivary stress biomarker level.
MATERIALS AND METHODS
Forty-six volunteers (23 men, 23 women) participated in this study. Bruxism behavior was assessed using a self-administered questionnaire, study casts, and BiteStrip, a miniature electronic screener used to detect sleep bruxism. The questionnaire consisted of six items asking about bruxism, occlusion, jaw functional limitation, and dentition. Occlusal wear was assessed from dental casts and calculated as the sum of the facets in the maxillary arch segment. Participants used BiteStrip at home for one night and the score was evaluated. Two-minute stimulated whole saliva samples were collected from participants to measure daytime levels of chromogranin A (CgA), a major salivary stress biomarker. Nonparametric tests of the relationship between variables were performed using the Spearman R and Kendall tau statistical correlation tests.
RESULTS
There was a positive correlation between self-reported bruxism and self-reported jaw functional limitation. Occlusal wear did not significantly correlate with occlusion, jaw functional limitation, or dentition, but it did significantly correlate with self-reported bruxism behavior, as well as the BiteStrip score. It was interesting to find that the CgA level was significantly negative in correlation with the BiteStrip score.
CONCLUSION
Sleep bruxism is believed to be a stress-related sleep disorder. The results suggest that daytime psychological stress level is significantly negative in correlation with sleep bruxism behavior.