EPIDEMIOLOGIC ASPECTS OF PRIMARY CNS TUMORS IN CHILDHOOD AND ADOLESCENCE - A POPULATION-BASED STUDY
EPIDEMIOLOGIC ASPECTS OF PRIMARY CNS TUMORS IN CHILDHOOD AND ADOLESCENCE - A POPULATION-BASED STUDY
复制标题
DOI：
10.1007/s002920050047
复制
发表时间：
1994-08-01
期刊：
影响因子：
--
通讯作者：
JANISCH, W
中科院分区：
文献类型：
--
作者：
STANECZEK, W;JANISCH, W
利用东德国家癌症登记处的记录，对1970-1989年期间儿童和青少年(0-20岁)的原发中枢神经系统肿瘤的发病率进行了调查。登记的这类肿瘤有2906例。93.2%的病例经组织病理学证实。男性发病率为31.0/100万，女性发病率为25.9/10万。2719例(93.6%)位于椎管内，187例(6.4%)位于椎管内。在调查期间，中枢神经系统肿瘤的发病率有所增加。这一增长在男性中更为明显，在女性人口中较少。最常见的肿瘤类型是胶质瘤(占所有登记的中枢神经系统肿瘤的38.7%)、髓母细胞瘤(14.0%)和室管膜瘤(10.9%)。130个原发中枢神经系统肿瘤发生在婴儿(1岁以下)。其中室管膜瘤21例，脉络丛肿瘤21例。
The incidence of primary CNS tumours in children and adolescents (0-20 years of age) was investigated for the time period 1970-1989 using the records of the East German National Cancer Registry. 2906 such tumours were registered. 93.2 % of them were histopathologically comfirmed. The incidence was 31.0/1 000 000 for the male and 25.9 for the female population. 2719 (93.6% of all tumours) were intracranially and only 187 (6.4%) intraspinally situated. The incidence of the CNS tumours increased during the time period of the investigation. This increase was more pronounced in the male and less in the female population. The most common tumour types were gliomas (38.7 % of all registered CNS tumours), medulloblastomas (14.0 %) and ependymomas (10.9%). 130 primary CNS tumours occurred in infants (less than 1 year of age). Among these tumours were 21 ependymomas and 21 choroid plexus tumours.