Adherence to medication treatment: A qualitative study of facilitators and barriers among a diverse sample of HIV+ men and women in four US cities
Adherence to medication treatment: A qualitative study of facilitators and barriers among a diverse sample of HIV+ men and women in four US cities
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DOI：
10.1023/a:1022513507669
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发表时间：
2003-03-01
影响因子：
4.4
通讯作者：
Le, GM
中科院分区：
文献类型：
--
作者：
Remien, RH;Hirky, AE;Le, GM
大多数检查艾滋病毒抗逆转录病毒药物治疗依从性的研究都涉及定量调查。尽管这些研究已经确定了与医疗依从性相关的因素，但没有任何单一变量或变量组合具有足够的一致性，可以适用于任何个人或人群。采用定性方法，对美国4个城市的不同种族的HIV阳性女性、男男性行为者和男性注射吸毒者（N = 110）进行了深入访谈，以了解他们在HIV药物依从性方面的知识、态度、信仰和经历，观点和生活背景。大多数人描述了对服药行为的多重影响，将依从性描述为一种动态现象，随着时间的推移，他们的信念、态度、情绪以及日常和更大的生活事件的变化而变化。普遍的主题包括对艾滋病毒药物的矛盾心理和故意不遵守，通常是为了解决身体副作用。来自不同领域的因素（例如，认知，情感，人际关系）可以有。代偿性影响行为结果。研究结果在社会行动理论方面进行了讨论，有助于我们对依从性现象的理论理解。
Most studies examining HIV antiretroviral medication treatment adherence involve quantitative surveys. Although these studies have identified factors associated with medical adherence, no single, variable or combination of variables is sufficiently consistent to apply to any individual or group of people. Using qualitative methods,an ethnically diverse sample (N = 110) of HIV+ women, men who have sex with men, and male injecting drug users in four U.S. cities were interviewed in depth to elicit their experiences, perspectives, and life contexts regarding knowledge, attitudes, beliefs, and experiences with HIV medication adherence. Most described multiple influences on medication-taking behavior, describing adherence as a dynamic phenomenon that changes over time with their changing beliefs, attitudes, emotions and daily and larger life events. Prevalent themes include ambivalence toward HIV medication and intentional nonadherence, usually to, address physical side-effects. Factors from different domains (e.g., cognitive, emotional, interpersonal) can have. compensatory influences on behavioral outcomes. Findings are discussed in terms of social action theory, contributing to our theoretical understanding of the phenomenon of adherence.