Rapid Flow Assessment of Congenital Heart Disease with High-Spatiotemporal-Resolution Gated Spiral Phase-Contrast MR Imaging
Rapid Flow Assessment of Congenital Heart Disease with High-Spatiotemporal-Resolution Gated Spiral Phase-Contrast MR Imaging
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DOI：
10.1148/radiol.11101844
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发表时间：
2011-07-01
期刊：
影响因子：
19.7
通讯作者：
Muthurangu, Vivek
中科院分区：
文献类型：
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作者：
Steeden, Jennifer A.;Atkinson, David;Muthurangu, Vivek
目的：在患有先天性心脏病的儿童和成人人群中验证通过敏感性编码（SENSE）加速的前瞻性触发螺旋相衬磁共振（MR）序列。材料和方法：当地研究伦理委员会批准了这项研究，并获得了所有患者或监护人的书面同意。对 40 名患者的每搏输出量进行了量化（平均年龄 +/- 标准差：21.4 岁 +/- 13.8，年龄范围：3.0-61.3 岁；22 名男性患者年龄 3.0-38.0 岁[平均年龄，17.2 岁 +/- 10.5]，18 名女性患者年龄 4.7-61.3 岁[平均年龄，26.6 岁 +/- 15.9]）患有主动脉（n = 40）、主肺动脉（n = 38）、右肺动脉（n = 22）和左肺动脉（n = 24）的先天性心脏病。每搏输出量通过以下方式获得：(a) 使用 SENSE 进行屏气螺旋相位对比 MR 成像，(b) 传统屏气笛卡尔相位对比 MR 成像，以及 (c) 参考自由呼吸相位对比 MR 成像。通过重复测量方差分析、Bland-Altman 分析和相关系数来比较每搏输出量。结果：屏气螺旋相衬 MR 序列的成像时间显着低于传统屏气相衬 MR 序列的成像时间（分别接近 5 秒和接近 16 秒；P < .0001）。参考自由呼吸序列（平均体积，60.3 mL +/- 27.3）和两个屏气序列-螺旋 SENSE 相衬 MR 成像（平均体积，59.5 mL +/- 27.1；P < .001）和传统笛卡尔相衬 MR 成像（平均体积，59.8 mL +/- 27.6；P = .268）。螺旋屏气序列的一致性限度比传统屏气序列的一致性限度更小（分别为-4.4 mL、2.9 mL vs -10.3 mL、9.3 mL）；相关性相似（分别为 r = 0.998 和 r = 0.984）。结论：使用螺旋 SENSE 相衬 MR 序列可以准确可靠地量化流量，并在短时间屏气时获得高时空分辨率。 (C) 北美放射学会，2011
Purpose: To validate a prospectively triggered spiral phase-contrast magnetic resonance (MR) sequence accelerated with sensitivity encoding (SENSE) in a population of children and adults with congenital heart disease.Materials and Methods: The local research ethics committee approved this study, and written consent was obtained from all patients or guardians. Stroke volumes were quantified in 40 patients (mean age +/- standard deviation: 21.4 years +/- 13.8, age range: 3.0-61.3 years; 22 male patients aged 3.0-38.0 years [mean age, 17.2 years +/- 10.5], 18 female patients aged 4.7-61.3 years [mean age, 26.6 years +/- 15.9]) with congenital heart disease in the aorta (n = 40), main pulmonary artery (n = 38), right pulmonary artery (n = 22), and left pulmonary artery (n = 24). Stroke volumes were obtained with (a) breath-hold spiral phase-contrast MR imaging with SENSE, (b) conventional breath-hold cartesian phase-contrast MR imaging, and (c) reference free-breathing phase-contrast MR imaging. Stroke volumes were compared by using repeated-measures analysis of variance, Bland-Altman analysis, and correlation coefficients.Results: Imaging time with the breath-hold spiral phase-contrast MR sequence was significantly lower than that with the conventional breath-hold phase-contrast MR sequence (similar to 5 seconds vs similar to 16 seconds, respectively; P < .0001). There was excellent agreement in stroke volumes in all vessels between the reference free-breathing sequence (mean volume, 60.3 mL +/- 27.3) and the two breath-hold sequences-spiral SENSE phase-contrast MR imaging (mean volume, 59.5 mL +/- 27.1; P < .001) and conventional cartesian phase-contrast MR imaging (mean volume, 59.8 mL +/- 27.6; P = .268). The limits of agreement were smaller with the spiral breath-hold sequence than with the conventional breath-hold sequence (-4.4 mL, 2.9 mL vs -10.3 mL, 9.3 mL, respectively); correlation was similar (r = 0.998 vs r = 0.984, respectively).Conclusion: Flow volumes can be accurately and reliably quantified by using a spiral SENSE phase-contrast MR sequence, with high spatiotemporal resolution obtained in a short breath hold. (C) RSNA, 2011