Glucanhydrolase from Lipomyces starkeyi KSM 22 as potential mouthwash ingredient
Glucanhydrolase from Lipomyces starkeyi KSM 22 as potential mouthwash ingredient
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来自斯达克油脂酵母 KSM 22 的葡聚糖水解酶可作为潜在的漱口水成分
DOI：
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发表时间：
2002
期刊：
影响因子：
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通讯作者：
D. Day
中科院分区：
文献类型：
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作者：
Doman Kim;S. Ryu;Eun;Hyunju Chung;Seung;Do Won Kim;D. Day
来自斯塔克油脂酵母 KSM 22 的葡聚糖水解酶（一种具有右旋糖酐分解和淀粉分解活性的 DXAM 酶）可水解具有 α-(1→3)-、α-(1→4)- 和 α-(1→6)-D-糖苷键的多糖。在 3 周不刷牙的情况下，检查了含 DXAMase 漱口水的口腔卫生益处与人类实验性牙龈炎的关系。与洗必太治疗组相比，DXAMase 治疗组的牙菌斑积累和牙龈指数评分增幅较低。 DXAMase 处理组还表现出较少的舌头积聚、不良味觉和牙齿染色，从而表明 DXAMase 作为抗牙菌斑剂成分具有积极作用。
A glucanhydrolase (a DXAMase exhibiting both dextranolytic and amylolytic activities) from Lipomyces starkeyi KSM 22 hydrolyzed polysaccharides having α-(1→3)-, α-(1→4)-, and α-(1→6)-D-glucosidic linkages. The oral hygiene benefits of DXAMase-containing mouthwash were examined in relation to human experimental gingivitis during a 3-week period without brushing. The DXAMase-treated group exhibited a lower increase in plaque accumulation and gingival index score than the chlorhexidine-treated group. The DXAMase-treated group also showed less tongue accumulation, bad taste, and tooth staining, thus indicating a positive role for DXAMase as an antiplaque agent ingredient.