Increased prevalence of genotype F hepatitis B virus isolates in Buenos Aires, Argentina
Increased prevalence of genotype F hepatitis B virus isolates in Buenos Aires, Argentina
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阿根廷布宜诺斯艾利斯 F 基因型乙型肝炎病毒分离株流行率增加
DOI：
10.1128/jcm.35.7.1873-1875.1997
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发表时间：
1997
影响因子：
9.4
通讯作者：
R. H. Campos
中科院分区：
文献类型：
--
作者：
P. F. Telenta;Gustavo Palacios Poggio;José L. López;Jorge Gonzalez;Abraham Lemberg;R. H. Campos
对居住在阿根廷布宜诺斯艾利斯的12例HBsAg阳性携带者血清中的B型肝炎表面抗原（HBsAg）基因组编码区进行部分测序。系统发育分析将12株分离株分为基因型A（n = 4）、B（n = 1）、D（n = 2）和F（n = 5）。考虑到研究人群主要来自欧洲，基因型A和D的发生并不意外。F基因型及其遗传组成的高患病率支持F菌株起源于新大陆的土著人群的建议。
The genomic coding region of the hepatitis B surface antigen (HBsAg) was partially sequenced from 12 HBsAg-positive sera of carriers residing in Buenos Aires, Argentina. A phylogenetic analysis groups the 12 isolates into genotypes A (n = 4), B (n = 1), D (n = 2), and F (n = 5). The occurrence of genotypes A and D is not unexpected, considering the mainly European origin of the studied population. The high prevalence of genotype F and its genetic composition support the suggestion that F strains originated in native populations of the New World.