Sex-hormone-binding globulin early in pregnancy for the prediction of severe gestational diabetes mellitus and related complications
Sex-hormone-binding globulin early in pregnancy for the prediction of severe gestational diabetes mellitus and related complications
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DOI：
10.1111/j.1447-0756.2012.01870.x
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发表时间：
2012-11-01
影响因子：
1.6
通讯作者：
Demirtas, Selda
中科院分区：
文献类型：
--
作者：
Caglar, Gamze S.;Ozdemir, Elif D. U.;Demirtas, Selda
目的：本研究的目的是评估性激素结合球蛋白（SHBG）的诊断妊娠期糖尿病（GDM）的预测价值，并阐明SHBG水平和GDM并发症/药物需求之间的关联。材料和方法：在参与者（n = 93）谁提供的血液样本之间的13和16周的妊娠，30例随后发展GDM。记录并发症和医疗干预。计算SHBG的最佳临界点和诊断性能。结果：平均年龄为28.45 ± 5.0岁。GDM组（n = 30）的SHBG水平低于非GDM组（n = 63）（
Aims: The aim of this study was to evaluate the predictive value of sex-hormone-binding globulin (SHBG) for the diagnosis of gestational diabetes mellitus (GDM), and to clarify the association between SHBG levels and GDM complications/medication requirements.Material and Methods: Among the participants (n = 93) who provided blood samples between 13 and 16 weeks' gestation, 30 cases subsequently developed GDM. Complications and medical interventions were noted. The best cut-off point of SHBG and diagnostic performance were calculated.Results: The mean age was 28.45 +/- 5.0 years. SHBG levels were lower in the GDM group (n = 30) when compared with non-GDM (n = 63) cases (