Benefits from hazards, benefits from nothing, and benefits from benefits: the combined effects of five quaternary ammonium compounds to Vibrio qinghaiensis Q67
Benefits from hazards, benefits from nothing, and benefits from benefits: the combined effects of five quaternary ammonium compounds to Vibrio qinghaiensis Q67
复制标题
有危害、无益处、有好处：五种季铵化合物对青海弧菌Q67的综合作用
DOI：
10.1186/s12302-020-00310-z
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发表时间：
2020-03
影响因子：
5.9
通讯作者：
Zeng Hong-Hu
中科院分区：
文献类型：
--
作者：
Mo Ling-Yun;Liu Yong-An;Zhu Jie;Qin Li-Tang;Liang Yan-Peng;Zeng Hong-Hu
背景
多季铵化合物(QAC)共暴露广泛存在于水环境中。关于它们在低浓度下对微生物的毒性，目前还缺乏相关知识。本研究以青海弧菌Q67(暴露12h)为研究对象，采用长期微量板毒性分析方法(L-MTA)，研究了该菌对QAC单独和混合作用的毒性反应。
结果
在青海弧菌Q67暴露12h时，观察了5个单独的QAC的刺激效应。339.66%的−在0.00561摩尔/L四乙基溴化铵溶液中的刺激作用最强。当五组分混合物中的每一种QAC以50%的有效浓度存在时，检测到刺激效应(−23.55%)。此外，在零效点浓度(“零受益”)下，五种QAC联合使用的刺激效果显著(−为96.28%)。此外，当每个QAC以其最大刺激效应浓度联合暴露时，观察到显著的刺激效应(−406.16%)。这一现象被称为“受益于利益”。
结论
结果表明，无论是单一的还是混合的QAC都表现出兴奋效应。观察了QAC混合物的危害益处、无益处和益处。
Background
Co-exposure of multiple quaternary ammonium compounds (QACs) is widely present in the aquatic environment. The knowledge about their toxicities to microorganism at low concentration is lacking. This study aims to test the toxic response of Vibrio qinghaiensis Q67 (12-h exposure) to individual and mixtures of QACs by the long-term microplate toxicity analysis method (L-MTA).
Results
Hormetic effects were observed for five individual QACs at 12-h exposure of Vibrio qinghaiensis Q67. The maximum stimulation effect of − 339.66% was present in the 0.00561 mol/L tetraethylammonium bromide solution. A stimulation effect (− 23.55%) was detected when each of QACs in the five-component mixture was present at 50% effect concentration (“benefits from hazards”). In addition, significant stimulation effects (− 96.28%) were observed for five QACs combined at the zero-effect point concentration (“benefits from nothing”). Further, a significant stimulation effect (− 406.16%) was observed when each of QACs was co-exposed at its maximum stimulation effect concentration. This phenomenon was termed “benefits from benefits”.
Conclusions
The results suggest that both single and mixture of QACs presented hormetic effects. Benefits from hazards, benefits from nothing, and benefits from benefits were observed for the QACs mixtures.
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影响因子：
5.3
作者：
通讯作者：
--
影响因子：
2.8
作者：
A C Upton
通讯作者：
A C Upton
影响因子：
8.8
作者：
Bain, Peter A.;Kumar, Anupama
通讯作者：
Kumar, Anupama
影响因子：
10.4
作者：
Rajapakse N;Silva E;Kortenkamp A
通讯作者：
Kortenkamp A
DOI：
10.1016/j.scitotenv.2018.04.023
发表时间：
2018-09
期刊：
The Science of the total environment
影响因子：
--
作者：
Ya-Qian Xu;Shu-Shen Liu;Ye Fan;Kai Li
通讯作者：
Ya-Qian Xu;Shu-Shen Liu;Ye Fan;Kai Li