Visual evoked responses in humans with abnormal visual experience.
Visual evoked responses in humans with abnormal visual experience.
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具有异常视觉体验的人类的视觉诱发反应。
DOI：
10.1113/jphysiol.1975.sp010953
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发表时间：
1975
期刊：
影响因子：
--
通讯作者：
L. Thibos
中科院分区：
文献类型：
--
作者：
R. Freeman;L. Thibos
1.本文研究了正常人和弱视患者对不同空间频率光栅靶的视觉诱发反应。这种情况下，降低视觉分辨率为特定的目标方向，是相关的，并认为是由显着的眼睛散光。2.对于正常受试者，空间频率和诱发反应之间的一般关系类似于心理物理对比敏感度数据。对倾斜光栅的诱发响应幅度通常减小，并且这类似于与水平和垂直细节相比倾斜的较低敏锐度。3.除了倾斜效应外，视神经性弱视的诱发反应幅度取决于测试的大部分空间频率范围（0 - 5 - 16周/度）内的光栅方向。最低的诱发振幅时，发现刺激光栅方向匹配的敏锐度降低。4.诱发电位的空间频率响应函数是定性相似的对比敏感度函数确定与相同的异常主体。5.从这些结果，可以得出结论，视神经性弱视的生理位点主要局限于诱发电位产生部位或之前的结构。
1. The visual evoked response to a grating target of varying spatial frequency was examined for normal subjects and for subjects with meridional amblyopia. This condition, reduced visual resolution for specific target orientations, is associated with, and thought to result from, marked ocular astigmatism. 2. For normal subjects, the general relation between spatial frequency and the evoked response is similar to psychophysical contrast sensitivity data. Evoked response amplitudes to oblique gratings are typically reduced and this is analogous to the lower acuity for oblique compared to horizontal and vertical detail. 3. In addition to the oblique effect, the magnitude of the evoked response for meridional amblyopes depends upon grating orientation over most of the spatial frequency range tested (0‐5‐16 cycles/deg). The lowest evoked amplitude is found when stimulus grating orientation matches that for which acuity is reduced. 4. The evoked potentials spatial frequency response functions are qualitatively similar to contrast sensitivity functions determined with the same abnormal subjects. 5. From these results, it may be concluded that the physiological locus of meridional amblyopia is confined primarily to structures at or prior to the site of evoked potential generation.