Cocirculation of Three Hemagglutinin and Two Neuraminidase Subtypes of Avian Influenza Viruses in Huzhou, China, April 2013: Implication for the Origin of the Novel H7N9 Virus

Cocirculation of Three Hemagglutinin and Two Neuraminidase Subtypes of Avian Influenza Viruses in Huzhou, China, April 2013: Implication for the Origin of the Novel H7N9 Virus
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DOI:
10.1128/jvi.03319-13
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发表时间:
2014-06-01
影响因子:
5.4
通讯作者:
Zhang, Chiyu
Zhang, Chiyu
中科院分区:
医学2区
文献类型:
--
作者:
Han, Jiankang;Wang, Lili;Zhang, Chiyu

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2013年4月,我们在中国湖州地区的禽类中检测到三种禽流感血凝素(HA)亚型(H7、H9和H5)和两种神经氨酸酶(NA)亚型(N9和N2),以及与H7N9相关的H9N9重组中间产物。我们的研究结果表明,湖州不仅是新型H7N9病毒的地理起源之一,而且共循环对未来的人类构成了潜在的威胁。
We detected three avian influenza hemagglutinin (HA) subtypes (H7, H9, and H5) and two neuraminidase (NA) subtypes (N9 and N2), as well as H7N9-related H9N9 reassortant intermediates, cocirculating among poultry in Huzhou, China, during April 2013. The results of our study reveal not only that Huzhou is one of the geographic origins of the novel H7N9 virus but also that cocirculation poses a potential threat to humans in the future.