Editors' Introduction to the Chronic Pancreatitis and Pancreatic Cysts Special Issue.
Editors' Introduction to the Chronic Pancreatitis and Pancreatic Cysts Special Issue.
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慢性胰腺炎和胰腺囊肿特刊的编辑简介。
DOI：
10.1007/s10620-017-4613-z
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发表时间：
2017
影响因子：
3.1
通讯作者：
Habtezion,Aida
中科院分区：
文献类型：
--
作者：
Park,WalterG;Habtezion,Aida
我们很高兴地介绍第三届年度特别补充消化疾病和科学致力于埃米特B。基夫，这不仅是一种智力上的奋进，也是一种个人上的满足，因为我们两人都有幸在斯坦福大学与埃米特一起工作。今年的增刊重点关注慢性胰腺炎和胰腺囊肿，这是胰腺疾病谱中选择的一个重点，因为胃肠病（GI）社区最近对这些病变的兴趣越来越大。虽然每种疾病都有独特和有趣的方面，但两者都是胰腺癌发展的公认风险因素。美国国立卫生研究院对这一风险的认识得到了两个独立的多中心联盟的奖励：一个是NCI/NIDDK赞助的慢性胰腺炎、糖尿病和胰腺癌研究联盟，另一个是NCI赞助的胰腺癌早期检测联盟（胰腺癌检测联盟）。通过这些财团和其他来自具有类似使命的基金会的资金来源，GI社区可以期待新的观察和数据，这将大大促进对这些疾病发病机制的理解。因此，本补充的目标是提供我们目前对这些疾病的概念的框架，并随后确定进一步预期研究将为关键问题提供答案的关键空白领域。
We are pleased to introduce the third annual special supplement to Digestive Diseases and Sciences dedicated to Emmet B. Keeffe, an endeavor not only intellectually but also personally satisfying since both of us have had the distinct privilege of working with Emmet as trainees at Stanford. This year’s supplement focuses on chronic pancreatitis and pancreatic cysts, a focus chosen among the spectrum of pancreatic disorders, due to the increasing recent interest in these lesions by the gastroenterological (GI) community. While there are unique and intriguing aspects to each condition, both are recognized risk factors for the development of pancreatic adenocarcinoma. Recognition of this risk by the National Institutes of Health was rewarded by a surge of targeted funding through the formation of two separate multicenter consortia: an NCI/NIDDK-sponsored consortium for the study of Chronic Pancreatitis, Diabetes and Pancreas cancer, and an NCI-sponsored consortium for the early detection of pancreatic cancer (Pancreatic Cancer Detection Consortium). Through these consortia and other funding sources from foundations with similar missions, the GI community can expect new observations and data that will significantly advance the understanding of the pathogenesis of these conditions. The goal of this supplement thus is to both provide a framework of our current conceptions of these diseases and subsequently identify key gap areas where further anticipated research will provide answers to key questions.