Spatial working memory and spatial attention rely on common neural processes in the intraparietal sulcus
Spatial working memory and spatial attention rely on common neural processes in the intraparietal sulcus
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DOI：
10.1016/j.neuroimage.2010.06.068
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发表时间：
2010-11-01
期刊：
影响因子：
5.7
通讯作者：
Cunnington, Ross
中科院分区：
文献类型：
--
作者：
Silk, Timothy J.;Bellgrove, Mark A.;Cunnington, Ross
我们记忆空间位置的能力（空间工作记忆）和我们将注意力集中到这些位置的能力（空间注意力）是两个基本且密切相关的认知过程。越来越多的行为证据表明，空间工作记忆和空间注意力共享共同的资源，而神经影像学研究显示，在调节这两种认知功能的神经区域中存在一些重叠。目前的研究使用fMRI直接检查空间工作记忆和空间注意力依赖于共同的潜在神经机制的程度。在工作记忆保持间隔期间结合视觉搜索任务的空间工作记忆工作记忆和视觉搜索任务负荷被参数化调制。前额叶、运动前区和顶叶区域的广泛网络显示出随着空间工作记忆负荷的增加而增加的活动。在这些区域中，右缘上回的一部分，位于沿着顶叶内沟，显示出显著的相互作用，使得与空间工作记忆负荷相关的神经活动随着双重任务中视觉搜索负荷的增加而显著减弱。这种相互作用表明，沿着顶内沟的这部分缘上回，对于调节空间工作记忆和空间注意力转移至关重要。(C)2010年爱思唯尔公司版权所有
Our ability to remember locations in space (spatial working memory) and our ability to direct attention to those locations (spatial attention) are two fundamental and closely related cognitive processes. A growing body of behavioural evidence suggests that spatial working memory and spatial attention share common resources, while neuroimaging studies show some overlap in the neural regions that mediate these two cognitive functions The current study used fMRI to directly examine the extent to which spatial working memory and spatial attention rely on common underlying neural mechanisms Twenty healthy participants underwent functional MRI while performing a dual task of spatial working memory incorporating a visual search task during the working memory retention interval Working memory and visual search task loads were parametrically modulated A wide network of prefrontal, premotor, and parietal regions showed increasing activity with increased spatial working memory load Of these areas, part of the right supramarginal gyrus, lying along the intraparietal sulcus, showed a significant interaction such that the neural activity associated with spatial working memory load was significantly attenuated as visual search load in the dual task was increased This interaction suggests that this part of the supramarginal gyros, along the intraparietal sulcus, is critical for mediating both spatial working memory and shifts in spatial attention. (C) 2010 Elsevier Inc. All rights reserved