Head circumference measurements in children with autism
Head circumference measurements in children with autism
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DOI：
10.1177/088307389601100509
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发表时间：
1996-09-01
影响因子：
1.9
通讯作者：
Gartside, P
中科院分区：
文献类型：
--
作者：
Davidovitch, M;Patterson, B;Gartside, P
为了评估自闭症儿童的头围，回顾性分析了148张图表。所有的儿童都符合精神疾病诊断和统计手册（DSM-III或DSM-III-R）的自闭症标准，并且没有已知的可能影响头围的潜在疾病。此外，还收集了关于身高、体重、脑成像、认知发育、适应行为和语言的数据。这些儿童被分为两组：头围等于或高于第98百分位数的儿童（第1组）和头围低于第98百分位数的儿童（第2组）。第1组包括27名儿童（18.2%）。第1组的身高测量值显著高于第2组（P = .0006），体重测量值也显著高于第2组（P = .0003）。与第2组相比，第1组的女性比例（P = 0.04）和适应行为评分（P = 0.0067）显著降低。常规脑成像研究无法解释第1组中的大头畸形。自闭症儿童头围增大和生长指数增加的病因尚不清楚。
To assess head circumference in children with autism, 148 charts were retrospectively reviewed. All of the children met the Diagnostic and Statistical Manual of Mental Disorders (DSM-III or DSM-III-R) criteria for autism and had no known underlying condition that might affect head circumference. In addition, data were collected regarding height, weight, brain imaging, cognitive development, adaptive behavior, and language. The children were divided into two groups: those with head circumference at or above the 98th percentile (Group 1) and those with head circumference below the 98th percentile (Group 2). Group 1 consisted of 27 (18.2%) of the children. Height measurements were significantly higher in Group 1 as compared with Group 2 (P = .0006) as were weight measurements (P = .0003). Group 1 had a significantly lower percentage of females (P = .04) and lower adaptive behavior scores (P = .0067) than Group 2. Routine brain imaging studies could not explain the macrocephaly in Group 1. The etiology of large head circumference and increased growth indices in children with autism is unclear.