Evolution amplified processing with temporally dispersed slow neuronal connectivity in primates
Evolution amplified processing with temporally dispersed slow neuronal connectivity in primates
复制标题
DOI：
10.1073/pnas.0907655106
复制
发表时间：
2009-11-17
影响因子：
11.1
通讯作者：
Innocenti, Giorgio M.
中科院分区：
文献类型：
--
作者：
Caminiti, Roberto;Ghaziri, Hassan;Innocenti, Giorgio M.
胼胝体（corpus callosum，CC）是大脑两个半球之间进行交流的主要途径。在猴子、黑猩猩和人类中，不同大小的胼胝体轴突连接功能不同的皮质区域。较薄的轴突在腹侧和在后体的CC互连的前额叶和顶叶区，分别和较厚的轴突在中体和压互连初级运动，躯体感觉和视觉领域。与猕猴相比，黑猩猩的轴突直径和传导速度在所有位置都略有增加，这是因为大轴突的数量增加了，但黑猩猩和人类之间的轴突却没有增加，这一点，再加上大大脑中更长的连接，使预期的两个半球之间的传导延迟增加了一倍，从猕猴到人类，其范围扩大了约3倍。这些变化可能会对皮质动力学产生一些影响，特别是对半球间振荡器的周期。
The corpus callosum (CC) provides the main route of communication between the 2 hemispheres of the brain. In monkeys, chimpanzees, and humans, callosal axons of distinct size interconnect functionally different cortical areas. Thinner axons in the genu and in the posterior body of the CC interconnect the prefrontal and parietal areas, respectively, and thicker axons in the midbody and in the splenium interconnect primary motor, somatosensory, and visual areas. At all locations, axon diameter, and hence its conduction velocity, increases slightly in the chimpanzee compared with the macaque because of an increased number of large axons but not between the chimpanzee and man. This, together with the longer connections in larger brains, doubles the expected conduction delays between the hemispheres, from macaque to man, and amplifies their range about 3-fold. These changes can have several consequences for cortical dynamics, particularly on the cycle of interhemispheric oscillators.