Sequential computed tomographic imaging of a transplantable rabbit brain tumor.
Sequential computed tomographic imaging of a transplantable rabbit brain tumor.
复制标题
可移植兔脑肿瘤的连续计算机断层扫描成像。
DOI：
10.1007/bf00341774
复制
发表时间：
1986
期刊：
影响因子：
2.8
通讯作者：
Anderson,J
中科院分区：
文献类型：
--
作者：
Kumar,AJ;Hassenbusch,S;Rosenbaum,AE;Beck,TJ;Hadfield,R;Ahn,HS;Anderson,J
评估CT成像评价兔脑VX-2肿瘤生长的准确性。5只远交种新西兰白兔在额顶叶植入3x105个活的VX-2肿瘤细胞前、4、7、9和13天（3只动物）进行CT扫描。CT检查结果与大体病理相关。5只兔在植入后第9天CT显示肿瘤，肿瘤大小为4-6x3-4x2-3 mm。第9 ~ 13天，2只兔肿瘤增大6倍，第3只兔肿瘤增大12倍。CT是评估该模型中脑肿瘤生长的有用技术，在记录化疗对肿瘤生长的影响方面应具有价值。
The accuracy of CT imaging in evaluating VX-2 tumor growth in the rabbit brain was assessed. CT scanning was performed in 5 outbred New Zealand white male rabbits before and at 4, 7, 9 and 13 (in 3 animals) days after surgical implantation of 3x105viable VX-2 tumor cells in the frontoparietal lobes. The CT studies were correlated with gross pathology in each. The tumor was visualized with CT in all 5 rabbits by the 9th day post implantation when the tumor ranged in size from 4–6x3–4x2–3 mm. Between the 9th and 13th day, the tumor increased 6-fold in two rabbits and 12-fold in the third rabbit. CT is a useful technique to evaluate brain tumor growth in this model and should be valuable in documenting the efficacy of chemotherapy on tumor growth.