Monitoring sarcomere structure changes in whole muscle using diffuse light reflectance.
Monitoring sarcomere structure changes in whole muscle using diffuse light reflectance.
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DOI：
10.1117/1.2234278
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发表时间：
2006-07
影响因子：
3.5
通讯作者：
J. Xia;A. Weaver;D. Gerrard;G. Yao
中科院分区：
文献类型：
--
作者：
J. Xia;A. Weaver;D. Gerrard;G. Yao
横纹肌的正常生物力学和生理功能是由重复的肌节单位促进的。光散射技术已被用于研究单个提取的肌纤维。然而，很少有研究，如果有的话，已经进行了调查的可能性，使用光学检测检查肌节结构的变化，在整个肌肉。我们进行了一系列的实验，以证明在整个肌肉中测量的光散射特性与肌节结构的变化有关。这些结果表明，光子迁移技术具有潜在的特点，在整个肌肉的组织超微结构的变化在体内。
Normal biomechanical and physiological functions of striated muscles are facilitated by the repeating sarcomere units. Light scattering technique has been used in studying single extracted muscle fibers. However, few studies, if any, have been conducted to investigate the possibility of using optical detection to examine sarcomere structure changes in whole muscles. We conducted a series of experiments to demonstrate that optical scattering properties measured in whole muscle are related to changes in sarcomere structure. These results suggest that photon migration technique has a potential for characterizing in vivo tissue ultrastructure changes in whole muscle.