A prognostic index to predict long-term mortality in patients with mild to moderate chronic heart failure stabilised on angiotensin converting enzyme inhibitors
A prognostic index to predict long-term mortality in patients with mild to moderate chronic heart failure stabilised on angiotensin converting enzyme inhibitors
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DOI：
10.1016/s1388-9842(03)00053-9
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发表时间：
2003-08-01
影响因子：
18.2
通讯作者：
Fox, KAA
中科院分区：
文献类型：
--
作者：
Kearney, MT;Nolan, J;Fox, KAA
背景：轻中度慢性心力衰竭患者的死亡率仍然很高。目前还没有一种简单的方法来确定这一人群中长期死亡风险增加的患者。目的：建立一种预后指标，以识别死亡风险增加的轻中度慢性心力衰竭门诊患者。方法和结果：1993年12月至1995年4月，553例平均（S.D.）年龄63（+/-10）岁，有慢性心力衰竭症状（纽约心脏协会功能等级平均2.3(+/-0.5)）的门诊患者被招募。到2000年4月，已有201名患者死亡。利用无创测量心脏大小、电和自主神经功能、肾功能和血浆生化的数据，我们确定了8个独立的死亡率预测因子(均为P
Background: Mortality in patients with mild to moderate chronic heart failure remains high. At present there is no easy way of identifying patients within this population at increased risk of death in the medium to long term. Aims: To develop a prognostic index to identify outpatients with mild to moderate chronic heart failure at increased risk of death. Methods and results: Five hundred and fifty-three outpatients mean (S.D.) age 63(+/-10) years with symptoms of chronic heart failure (mean New York Heart Association functional class, 2.3( +/-0.5)), were recruited between December 1993 and April 1995. By April 2000, 201 patients had died. Using data from non-invasive measurements of cardiac size, electrical and autonomic function, renal function and plasma biochemistry we identified eight independent predictors of mortality (all P