Enantioselective organocatalytic Michael addition of isorhodanines to alpha,beta-unsaturated aldehydes
Enantioselective organocatalytic Michael addition of isorhodanines to alpha,beta-unsaturated aldehydes
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异罗丹宁与 α,β-不饱和醛的对映选择性有机催化迈克尔加成
DOI:
10.1039/c5ob02457a
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发表时间:
2016
影响因子:
3.2
通讯作者:
Sheng Chunquan
中科院分区:
文献类型:
--
作者:
Wu Shanchao;Li Yu;Zhang Yongqiang;Fang Kun;Dong Guoqiang;Liu Na;Miao Zhenyuan;Yao Jianzhong;Wang Wei;Zhang Wannian;Sheng Chunquan
The Michael reaction of substituted isorhodanines with α,β-unsaturated aldehydes in the presence of a catalytic amount of a chiral secondary amine is presented. This transformation proceeds in good to high yields furnishing the corresponding 4,5-disubstituted isorhodanine adducts in good to excellent enantioselectivities.