Coronary Events Caused by Myocardial Bridge
Coronary Events Caused by Myocardial Bridge
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发表时间：
2009
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通讯作者：
Y. Ishikawa;Y. Kawawa;E. Kohda;T. Ishii
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作者：
Y. Ishikawa;Y. Kawawa;E. Kohda;T. Ishii
心肌桥是冠状动脉主干在心外膜下脂肪组织中走行的一部分在壁内形成的一种正常解剖变异。2)它几乎完全位于左前降支冠状动脉（LAD）的中部。4)早在1960年，冠状动脉造影就已证实MB对冠状动脉粥样硬化具有抑制作用，而内膜病变在MB近端的动脉段中进展。然而，MB与临床症状的相关性迄今为止一直存在争议。尽管MB的存在长期以来被认为是冠心病（CHD）（包括心绞痛、心肌缺血、心肌梗死和心源性猝死）的良性疾病，但最近的技术，如血管内超声（IVUS）、冠状动脉内多普勒（ICD）和多层螺旋CT（MSCT），已导致症状性MB病例报告的增加。几项研究也记录了甲基溴与冠心病的关系。6，12，13）此外，我们最近的尸检研究通过心肌桥心脏中具有MB的LAD的组织形态计量学阐明了MB在心肌梗死发生中的作用（1）心肌桥引起的冠状动脉事件
The myocardial bridge (MB) is a normal anatomical variant under which a part of the major coronary arteries usually running in the subepicardial adipose tissue courses intramurally. 2) It is almost exclusively situated in the mid-portion of left anterior descending coronary artery (LAD). 4) Coronary angiography has demonstrated a suppressive effect on coronary atherosclerosis by MB as early as 1960, whereas intimal lesion progresses in the arterial segment proximal to MB. However, the relevance of MB to clinical symptoms has been so far controversial. Although the MB presence has long been considered benign for coronary heart diseases (CHDs) 8) including angina, myocardial ischemia, myocardial infarction and sudden cardiac death, the recent techniques such as intravascular ultrasound (IVUS), intracoronary doppler (ICD) and multislice spiral computed tomography (MSCT) have led to an increase of case reports on symptomatic MB. Several studies have also documented the association of MB with CHDs. 6, 12, 13) Moreover, our recent autopsy study elucidated the role of MB on the occurrence of myocardial infarction through histomorphometry for LAD having MB in hearts with myocardial (1) Coronary Events Caused by Myocardial Bridge