INFLUENCE OF BIRTH-WEIGHT ON ADULT BONE-MINERAL DENSITY
INFLUENCE OF BIRTH-WEIGHT ON ADULT BONE-MINERAL DENSITY
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DOI：
10.1007/bf01623168
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发表时间：
1993-01-01
影响因子：
4
通讯作者：
HOWEY, S
中科院分区：
文献类型：
--
作者：
HAMED, HM;PURDIE, DW;HOWEY, S
骨矿物质密度 (BMD) 在生长过程中不断增加，直至成熟时达到峰值。绝经后骨质疏松症的风险取决于骨密度峰值及其随后的损失率。为了确定出生时低体重是否会影响峰值骨密度，我们使用双能 X 射线骨密度仪 (DXA) 测量了一组出生时低体重的妇女和正常出生体重的对照组的腰椎和股骨颈的 BMD。出生体重与成人骨密度之间无显着相关性。因此，出生时的低体重似乎不会影响骨密度峰值，而且早产也不是骨质疏松症的危险因素。
Bone mineral density (BMD) increases during growth until a peak is reached at maturity. The risk of development of postmenopausal osteoporosis depends on the peak bone density and the rate of its subsequent loss. To identify whether low weight at birth could affect the peak bone density, we measured BMD at both the lumbar spine and femoral neck using dual energy X-ray absorptiometry (DXA) in a group of women who had low weight at birth and in a control group of normal birth weight. There was no significant correlation between the weight at birth and the adult BMD. It appears, therefore, that low weight at birth does not influence the peak bone density and that prematurity is not a risk factor for osteoporosis.