Carbon nanotube electron field emitters for x-ray imaging of human breast cancer.
Carbon nanotube electron field emitters for x-ray imaging of human breast cancer.
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DOI：
10.1088/0957-4484/25/24/245704
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发表时间：
2014-06-20
期刊：
影响因子：
3.5
通讯作者：
Zhou O
中科院分区：
文献类型：
--
作者：
Gidcumb E;Gao B;Shan J;Inscoe C;Lu J;Zhou O
对于人类乳腺癌成像，与 2D 乳房 X 光检查相比，数字乳腺断层合成 (DBT) 已被证明可以提高图像质量和乳腺癌检测。当前的 DBT 系统空间分辨率有限且扫描时间较长。固定式数字乳腺断层合成 (s-DBT) 利用一系列碳纳米管 (CNT) 场发射 X 射线源，可提供比当前 DBT 系统更高的空间分辨率和更快的成像速度。本研究介绍了用于 X 射线乳腺成像任务的 CNT 阴极的详细评估结果。研究了以下内容：用于 DBT 的 CNT 阴极的高电流、长期稳定性；使用 CNT 阴极执行 2D 射线照相功能的可行性；以及经过多年成像的阴极性能。结果表明，使用 CNT 阴极的乳房断层合成系统的运行时间远远超过实验测试的一到两年的寿命。研究发现 CNT 阴极能够产生比典型 DBT 所需的更高的电流，这表明 s-DBT 成像时间可以进一步缩短。证明了使用 s-DBT 管的单阴极在 4 秒内进行 2D 乳房 X 线摄影的可行性。在原型 s-DBT 系统的整个生命周期中，我们发现阴极性能和传输速率均稳定且一致。
For imaging human breast cancer, digital breast tomosynthesis (DBT) has been shown to improve image quality and breast cancer detection in comparison to 2D mammography. Current DBT systems have limited spatial resolution and lengthy scan times. Stationary digital breast tomosynthesis (s-DBT), utilizing an array of carbon nanotube (CNT) field emission X-ray sources, provides increased spatial resolution and potentially faster imaging than current DBT systems. This study presents the results of detailed evaluations of CNT cathodes for X-ray breast imaging tasks. The following were investigated: high current, long-term stability of CNT cathodes for DBT; feasibility of using CNT cathodes to perform a 2D radiograph function; and cathode performance through several years of imaging. Results show that a breast tomosynthesis system using CNT cathodes could run far beyond the experimentally tested lifetime of one to two years. CNT cathodes were found capable of producing higher currents than typical DBT would require, indicating that the s-DBT imaging time can be further reduced. The feasibility of using a single cathode of the s-DBT tube to perform 2D mammography in 4 seconds, was demonstrated. Over the lifetime of the prototype s-DBT system, it was found that both cathode performance and transmission rate were stable and consistent.
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