Association Between Atrial Fibrillation and the Risk of Cardiovascular Mortality Among Elderly Adults With Ischemic Stroke in Northeast China: A Community-Based Prospective Study.
Association Between Atrial Fibrillation and the Risk of Cardiovascular Mortality Among Elderly Adults With Ischemic Stroke in Northeast China: A Community-Based Prospective Study.
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DOI：
10.3389/fnagi.2022.836425
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发表时间：
2022
影响因子：
4.8
通讯作者：
Chen H
中科院分区：
文献类型：
--
作者：
Xia Z;Dang W;Jiang Y;Liu S;Yue L;Jia F;Sun Q;Shi L;Sun J;Li J;Chen H
老年人易患心房颤动（AF）和缺血性中风（IS）；然而，关于 AF 与 IS 老年人群心血管疾病 (CVD) 死亡风险之间的关系，人们知之甚少。我们的目的是调查患有 IS 的老年人中 AF 的特征，并说明 AF 是否导致 CVD 死亡率。基线时，2017年9月至2019年3月期间，纳入了790名来自中国东北老年人群（>60岁）的IS患者。分析了各年龄组房颤的患病率、知晓率和治疗情况，以及主要相关的心血管危险因素。对人群进行跟踪直至2021年7月31日，并获得了CVD死亡信息。共有 25 人患有 AF，患有 IS 的老年人群中 AF 患病率为 3.2%。房颤患病率随年龄增长而增加，从1%（60~64岁）上升至4.3%（70~74岁）和4.2%（≥75岁），其中城市居民高于农村居民（5.7% vs. 2.2%，P = 0.014）。 AF患者的知晓率和治疗率分别为80%和8%。中位随访期为 3.3 年后，58 名受试者因 CVD 死亡，5 名受试者伴有 AF（比率 70.6/1,000 人年）。与非 AF 参与者相比，在完全调整的模型中，患有 AF 的老年 IS 患者的 CVD 死亡风险增加了 3.65 倍。在患有 IS 的老年人群中，房颤患病率随着年龄的增长而增加。此外，中国东北地区患有 AF 的老年 IS 患者的 CVD 死亡率较高。因此，需要对东北地区患有IS的老年人群进行房颤的早期筛查和及时治疗。
Elderly people are susceptible to atrial fibrillation (AF) and ischemic stroke (IS); however, less information is known about the association between AF and the risk of cardiovascular disease (CVD) mortality in elderly population with IS. We aimed to investigate the features of AF among aged people with IS and to illustrate whether AF accounted for CVD mortality. At baseline, 790 patients with IS were enrolled from the general northeast Chinese elderly population (>60 years) between September 2017 to March 2019. The prevalence, awareness, and treatment of AF in each age group were analyzed, as well as major-related cardiovascular risk factors. The population was followed until July 31, 2021, and information on CVD death was obtained. A total of 25 people had AF, and the prevalence of AF in the elderly population with IS was 3.2%. The AF prevalence grew along with age from 1% (60–64 years) to 4.3% (70–74 years) and 4.2% (≥75 years), which was higher in the urban residents than in the rural residents (5.7 vs. 2.2%, P = 0.014). The awareness and treatment rates of patients with AF were 80 and 8%. After a median follow-up period of 3.3 years, 58 subjects died due to CVD and 5 subjects were accompanied with AF (rate 70.6/1,000 person-years). Elderly IS patients with AF had a 3.65-fold increased risk of CVD death in the fully adjusted model when compared with non-AF participants. The AF prevalence increased with age among the elderly population with IS. Moreover, elderly patients with IS in northeast China with AF had a higher CVD mortality. Therefore, early screening and prompt management of AF in elderly population with IS in northeast China are required.
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影响因子：
8.3
作者：
WOLF, PA;ABBOTT, RD;KANNEL, WB
通讯作者：
KANNEL, WB
影响因子：
39.3
作者：
Boehm, Michael;Cotton, Daniel;Diener, Hans-Christoph
通讯作者：
Diener, Hans-Christoph
影响因子：
24
作者：
Jose, Powell O.;Frank, Ariel T. H.;Palaniappan, Latha P.
通讯作者：
Palaniappan, Latha P.
心房颤动患者中风的机制和预防治疗。
影响因子：
8.2
作者：
Kim YH;Roh SY
通讯作者：
Roh SY
影响因子：
37.8
作者：
Fuster, Valentin;Ryden, Lars E.;Wann, L. Samuel
通讯作者：
Wann, L. Samuel