Non-opioid analgesics: Novel approaches to perioperative analgesia for major spine surgery
Non-opioid analgesics: Novel approaches to perioperative analgesia for major spine surgery
复制标题
DOI：
10.1016/j.bpa.2015.11.002
复制
发表时间：
2016-03-01
影响因子：
4.8
通讯作者：
Nemergut, Edward C.
中科院分区：
文献类型：
--
作者：
Dunn, Lauren K.;Durieux, Marcel E.;Nemergut, Edward C.
围手术期疼痛管理是脊柱大手术后的一个重大挑战。许多途径导致围手术期疼痛，包括伤害性、炎症性和神经性来源。虽然阿片类药物长期以来一直是围手术期镇痛的主要药物，但其他非阿片类药物疗法已越来越多地用作多模式镇痛方案的一部分，以改善疼痛控制，同时最大限度地减少阿片类药物相关的副作用。在这里，我们回顾了支持使用新型镇痛方法作为脊柱大手术静脉阿片类药物的替代方法的证据。(C)2015爱思唯尔有限公司版权所有。
Perioperative pain management is a significant challenge following major spine surgery. Many pathways contribute to perioperative pain, including nociceptive, inflammatory, and neuropathic sources. Although opioids have long been a mainstay for perioperative analgesia, other non-opioid therapies have been increasingly used as part of a multimodal analgesic regimen to provide improved pain control while minimizing opioid-related side effects. Here we review the evidence supporting the use of novel analgesic approaches as an alternative to intravenous opioids for major spine surgery. (C) 2015 Elsevier Ltd. All rights reserved.