Visuomotor coordination in the newt (triturus viridescens) after regeneration of the optic nerve
Visuomotor coordination in the newt (triturus viridescens) after regeneration of the optic nerve
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视神经再生后蝾螈（triturus viridescens）的视觉运动协调
DOI：
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发表时间：
1943
期刊：
影响因子：
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通讯作者：
R. Sperry
中科院分区：
文献类型：
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作者：
R. Sperry
已经表明，在视神经再生后，成年有尾目两栖动物可以恢复对小的移动物体进行准确空间定位的正常视力（Stone和Zaur，'40）。恢复视力的正常是由于再生的视神经纤维在它们原来连接的同一中枢神经元上的选择性突触终止，还是由于视神经纤维不加选择地再生后的纯粹功能性重组，仍然是一个问题。大量证据表明，再生神经纤维不显示选择性终止（兰利和桥本，'17 ; Dogliotti，'35;韦斯，'41 a ; Kilvington，'41）。另一方面，在视网膜视野旋转180度后，适应不良反应的固定持续性（Sperry，'43）表明有尾目动物视觉系统的功能组织中的极端刚性，并且似乎不相信再学习或其他功能适应过程方面的解释。然而，这两种解释都没有被明确排除，尤其是后者，因为
It has been shown that normal vision with accurate spatial localization of small moving objects may be recovered in adult urodele amphibians after regeneration of the optic nerve (Stone and Zaur, '40). Whether the normality of the restored vision is due to selcctive synaptic termination of the regenerating optic fibers on the same central neurons to which they were originally connected, or instead, to a purely functional reorganization after indiscriminate regeneration of the optic fibers has remained a problem. An explanation on the former basis has been disfavored by abundant evidence that regenerating nerve fibers do not show selective termination (Langley and Hashimoto, '17 ; Dogliotti, '35; Weiss, '41 a ; Kilvington, '41). On the other hand the fixed persistence of maladaptive reactions following 180 degree rotation of the retinal field (Sperry, '43) indicates an extreme rigidity in the functional organization of the visuomotor system of urodeles and would seem to discredit an explanation in terms of relearning or other functionally adaptive processes. Neither explanation has been definitely excluded, however, particularly the latter, since