Kinetic study of tumor blood flow in prostatic cancer using power Doppler imaging

Kinetic study of tumor blood flow in prostatic cancer using power Doppler imaging
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DOI:
10.1016/s0301-5629(98)00140-9
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发表时间:
1999-01-01
影响因子:
2.9
通讯作者:
Kojima, M
Kojima, M
中科院分区:
医学3区
文献类型:
--
作者:
Okihara, K;Watanabe, H;Kojima, M

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我们采用能量多普勒成像技术检查了11例前列腺癌去势前后肿瘤多普勒道信号和前列腺体积的变化,并比较了11例前列腺癌的血管阻力(RI)和前列腺体积(PV)的变化。除1例外,所有病例去势后RI和PV均下降,无一例外。两者的下降方式均呈指数曲线。然而,与PV相比,RI的下降时间在极窄的范围内,肿瘤血管血流受到去势的影响,导致RI的下降。血管血流的动态变化发生早于PV,分析肿瘤血流信号的变化可以为前列腺癌患者的早期治疗效果提供有价值的信息;然而,它可能不是预测预后的有用参数。 (C) 1998 年世界超声医学与生物学联合会。
We examined the changes in tumor Doppler dow signals as well as prostatic volume in 11 cases of prostatic cancer, before and after castration, by using power Doppler imaging, and compared the changes in vascular resistance (RI) and prostatic volume (PV) in 11 cases. RI, except for one case, and PV decreased after castration in all cases without exception. In both, the manner of decrease showed an exponential curve. However, the reduction time of RI fell in an extremely narrow range compared with that of PV, Tumor vascular flow was influenced by castration, resulting in a decrease of RI. The dynamic change of vascular flow occurred earlier than that of PV, Analysis of changes in tumor blood flow signals could offer valuable information on early therapeutic effects in patients with prostatic cancer; however, it might not be a useful parameter for the prediction of prognosis. (C) 1998 World Federation for Ultrasound in Medicine & Biology.