POSITRON EMISSION TOMOGRAPHY AND AUTORADIOGRAPHIC STUDIES OF GLUCOSE-UTILIZATION FOLLOWING ELECTROCONVULSIVE SEIZURES IN HUMANS AND RATS

POSITRON EMISSION TOMOGRAPHY AND AUTORADIOGRAPHIC STUDIES OF GLUCOSE-UTILIZATION FOLLOWING ELECTROCONVULSIVE SEIZURES IN HUMANS AND RATS
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DOI:
10.1111/j.1749-6632.1986.tb51260.x
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发表时间:
1986-03-14
影响因子:
5.2
通讯作者:
BAXTER, L
BAXTER, L
中科院分区:
综合性期刊3区
文献类型:
--
作者:
ACKERMANN, RF;ENGEL, J;BAXTER, L

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正电子发射断层扫描(PET)已与2-脱氧葡萄糖(2DG)方法的修改结合使用。目的:研究不同类型癫痫患者脑局部葡萄糖代谢的变化。3.~电休克疗法(ECT)诱发的癫痫发作似乎是PET研究的理想选择,因为它们在患者之间比许多其他类型的癫痫发作更均匀,并且它们的发生受到控制。然而,ECT癫痫发作尚未得到详细研究,也许是因为这些优点带来了一些不容易克服的方法学缺点。
Positron emission tomography (PET) has been used in conjunction with modifications of the 2-deoxyglucose (2DG) method'.'to study local brain glucose metabolism in a variety of human seizure~ yndromes. 3.~ It would seem that seizures induced by electroconvulsive therapy (ECT) are ideal for PET studies in that they are more uniform from patient to patient than many other types of seizures, and in that their occurrence is controlled. However, ECT seizures have not been studied in detail, perhaps because these advantages bring with them some methodological disadvantages that are not easily overcome.