Activation of Primary and Secondary Somatosensory Regions Following Tactile Stimulation of the Face
Activation of Primary and Secondary Somatosensory Regions Following Tactile Stimulation of the Face
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DOI：
10.1007/s00062-009-8022-3
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发表时间：
2009-06-01
影响因子：
2.8
通讯作者：
Wiesmann, Martin
中科院分区：
文献类型：
--
作者：
Kopietz, Rainer;Sakar, Vehbi;Wiesmann, Martin
背景：自从 Penfield 和 Rasmussen 的研究以来，人们已经确定人类初级体感皮层是按体位组织的。然而，面部表征的顺序仍然是一个值得讨论的问题，即，尚不清楚在体感皮层中面部是否被倒置或相反。 材料和方法：在功能性磁共振成像研究（n = 30）中，使用气动装置对面部每一侧的三个不同位置施加触觉刺激。刺激位置对应于三叉神经的三个分支（前额、脸颊、下巴）。为了确定面部在初级和次级体感皮层上的表征，对这些区域内的峰值坐标进行了个体分析。结果：在面部触觉刺激后发现初级体感皮层对侧激活，而次级体感皮层在双侧激活。然而，应用于一侧面部的不同触觉刺激的激活坐标之间的差异不具有统计学意义。结论：面部的触觉刺激导致对侧初级体感皮层的激活和双侧次级体感皮层的激活。使用作者的方法，不可能检测到与不同面部区域相关的体位组织。
Background: Since the work of Penfield & Rasmussen it is well established that the human primary somatosensory cortex is organized somatotopically. However, the order of the representation of the face is still a matter of discussion, i.e., it is yet unclear whether the face is represented upside-down or vice versa in the somatosensory cortex.Material and Methods: In a functional magnetic resonance imaging study (n = 30), tactile stimuli to three different locations on each side of the face were applied using a pneumatic device. Locations of stimulation corresponded to the three branches of the trigeminal nerve ( forehead, cheek, chin). To determine the representation of the face on primary and secondary somatosensory cortices, peak coordinates within these regions were analyzed subjectwise.Results: Contralateral activation of the primary somatosensory cortex following tactile stimulation of the face was found, whereas the secondary somatosensory cortices were activated bilaterally. However, differences between activation coordinates of different tactile stimuli applied to one side of the face were not statistically significant.Conclusion: Tactile stimulation of the face leads to contralateral activation of primary and bilateral activation of secondary somatosensory cortices. Using the authors' methodological approach it was not possible to detect a somatotopic organization related to different facial areas.