Assessment of the effectiveness of PMTCT program in eight service delivery points in North Central Nigeria
Assessment of the effectiveness of PMTCT program in eight service delivery points in North Central Nigeria
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DOI：
10.2147/hiv.s157685
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发表时间：
2018-01-01
影响因子：
1.5
通讯作者：
Taylor-Robinson, Simon David
中科院分区：
文献类型：
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作者：
Oleribe, Obinna Ositadimma;Enenche, Ede;Taylor-Robinson, Simon David
背景：母婴传播（MTCT）是婴儿感染HIV最常见的途径之一。为了实现无艾滋病毒的一代，应消除母婴传播艾滋病毒。尼日利亚13年前开始提供预防母婴传播服务，但它仍然占全球母婴传播负担的三分之一以上。我们着手探索和定义的有效性，在选定的网站中北部中心尼日利亚。方法：我们进行了回顾性的二次数据分析，在两个州的8个服务提供点。提取并分析了2012年至2016年的1454对母婴数据集。母亲/婴儿抗逆转录病毒（ARV）服务，早期婴儿诊断（EID），和最终的结果进行了审查，以检查在这些centers.Results的母婴传播的HIV的预测因素：我们检索到1,454母婴对数据集。虽然89.5%（1，302）的阳性孕妇（PPW）和92.2%（1，340）的艾滋病毒暴露婴儿（HEI）接受了抗逆转录病毒预防/抗逆转录病毒治疗（ART），但88.4%（1，285）的婴儿是母乳喂养的，32.5%在干血斑（DBS）采集时仍在接受母乳喂养。EID PCR阳性率为3.5%（0.0%~ 11.1%）。分娩便利度（χ 2 =24.99，P
Background: Mother-to-child transmission (MTCT) of HIV is one of the commonest avenues through which infants are infected with HIV. To achieve an HIV-free generation, MTCT of HIV should be eliminated. Nigeria began prevention of mother-to-child transmission (PMTCT) services 13 years ago, but it still contributes to over one-third of global MTCT burden. We set out to explore and define the effectiveness of PMTCT in selected sites in North Central Nigeria.Methods: We conducted a retrospective secondary data analysis at eight service delivery points in two states. One thousand four hundred and fifty-four mother-infant pair data sets from 2012 to 2016 were extracted and analyzed. Maternal/infant antiretroviral (ARV) services, early infant diagnosis (EID), and final outcomes were reviewed to examine the predictors of MTCT of HIV in these centers.Results: We retrieved 1,454 mother-infant pair data sets. While 89.5% (1,302) of positive pregnant women (PPW) and 92.2% (1,340) of HIV-exposed infants (HEIs) received ARV prophylaxis/ARV treatment (ART), 88.4% (1,285) infants were breastfed with 32.5% still receiving breast milk at the time of dry blood spot (DBS) collection. EID PCR positivity rate was 3.5% (range, 0.0%-11.1%). Facility of delivery (chi(2)=24.99, P