Delayed development of fear-potentiated startle in rats.
Delayed development of fear-potentiated startle in rats.
复制标题
大鼠恐惧增强惊吓的延迟发展。
DOI：
10.1037//0735-7044.108.1.69
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发表时间：
1994
影响因子：
1.9
通讯作者：
Campbell,BA
中科院分区：
文献类型：
--
作者：
Hunt,PS;Richardson,R;Campbell,BA
研究了16 - 75日龄大鼠恐惧增强惊吓的发育出现。在实验一中，纯音作为CS，声惊吓脉冲作为恐惧条件反射的非条件刺激（UCS）。在23日龄及以上的大鼠中观察到由CS音引起的恐惧增强惊吓，但在16日龄的大鼠中未观察到。在实验2中，一盏灯作为CS。30日龄及以上的大鼠表现出恐惧增强的惊吓，而23日龄的大鼠则没有。最后的实验表明，另一个恐惧的行为指数，刺激引起的冻结，在发展中观察到的恐惧增强惊吓，证实了条件反射恐惧的训练程序的有效性。结果表明，恐惧增强惊吓是一个相对较晚出现的反应系统，平行于条件自主神经变化（如心率）的发展，而不是冻结。（PsycInfo数据库记录（c）2022阿帕，保留所有权利）
Examined the developmental emergence of fear-potentiated startle in rats ranging in age from 16 to 75 days. In Exp 1, a pure tone served as the CS and an acoustic startle pulse served as the unconditioned stimulus (UCS) for fear conditioning. Fear-potentiated startle by the tone CS was observed in rats 23 days of age and older but not in rats 16 days of age. In Exp 2, a light served as the CS. Rats 30 days of age and older showed fear-potentiated startle, whereas 23-day-old rats did not. The final experiment demonstrated that another behavioral index of fear, stimulus-elicited freezing, was observed earlier in development than fear-potentiated startle, confirming the effectiveness of the training procedure for conditioning fear. Results suggest that fear-potentiated startle is a relatively late-emerging response system, parallelling the development of conditioned autonomic changes (eg, heart rate) rather than that of freezing.(PsycInfo Database Record (c) 2022 APA, all rights reserved)