Novel N-sulfonamide trans-platinum complexes: synthesis, reactivity and in vitro evaluation

Novel N-sulfonamide trans-platinum complexes: synthesis, reactivity and in vitro evaluation
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DOI:
10.1039/c1md00070e
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发表时间:
2011-08-01
期刊:
影响因子:
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通讯作者:
Navarro-Ranninger, Carmen
Navarro-Ranninger, Carmen
中科院分区:
医学3区
文献类型:
--
作者:
Aleman, Jose;del Solar, Virginia;Navarro-Ranninger, Carmen

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In this work, we described for the first time the synthesis of trans-N-sulfonamide platinum complexes. The antiproliferative activity (GI(50), mu M) of these new compounds in human solid tumors cells was compared to cisplatin.