Low-Level Exposure to Air Pollution and Risk of Adverse Birth Outcomes in Hillsborough County, Florida
Low-Level Exposure to Air Pollution and Risk of Adverse Birth Outcomes in Hillsborough County, Florida
复制标题
DOI：
10.1097/jom.0b013e31828df013
复制
发表时间：
2013-05-01
影响因子：
3.2
通讯作者：
Mbah, Alfred K.
中科院分区：
文献类型：
--
作者：
Mainolfi, Maria B.;Salihu, Hamisu M.;Mbah, Alfred K.
目的：在这个回顾性队列研究中（1998年至2007年），分析了佛罗里达州Hillsborough的145,445例单胎活产婴儿，以阐明胎儿发病率与产前暴露于六种标准空气污染物之间的关系。方法：本研究基于三个相互关联的数据库：佛罗里达州医院出院记录、生命统计记录和环境保护局的空气污染气象数据。研究的主要结局是低出生体重、早产和小于胎龄。本研究采用结构方程模型和孕期分组来评估空气污染与孕妇出生结局的关系。结果：结构方程模型的潜在变量B值为0.35，表明孕期暴露于标准污染物可能与胎儿发病率有显著关系。结论：妊娠期暴露于标准空气污染物与胎儿发病结局相关。
Objective: In this retrospective cohort (1998 to 2007), 145,445 singleton live births in Hillsborough, Florida, were analyzed to elucidate the relationship between fetal morbidity and prenatal exposure to six criteria air pollutants. Methods: This study was based on three linked databases: Florida Hospital Discharge, vital statistics records, and air pollution meteorological data from the Environmental Protection Agency. The primary outcomes of interest were low birth weight, preterm births, and small for gestational age. This study used structural equation modeling and trimester groupings to evaluate the relationship between air pollution and birth outcomes of pregnant residents. Results: The latent variables of structural equation modeling yielded a significant B value of 0.35, indicating that exposure to the criteria pollutants in pregnancy may have a significant relationship to fetal morbidity. Conclusion: Exposure to criteria air pollutants in pregnancy is associated with fetal morbidity outcomes.