A 14/14 marker chromosome lymphocyte clone in ataxia telangiectasia.
A 14/14 marker chromosome lymphocyte clone in ataxia telangiectasia.
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共济失调毛细血管扩张症中的 14/14 标记染色体淋巴细胞克隆。
DOI：
10.1093/oxfordjournals.jhered.a108569
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发表时间：
1975
期刊：
影响因子：
--
通讯作者：
T. Kelly
中科院分区：
文献类型：
--
作者：
J. Rary;M. Bender;T. Kelly
在共济失调毛细血管扩张症患者中观察到一个淋巴细胞克隆，其核型为45，XY，具有14/14串联易位标记，其频率随时间变化。在来自皮肤活检的成纤维细胞培养物中未观察到具有标记染色体的细胞，在来自患者的两个受影响同胞的白细胞培养物中也未观察到标记染色体。
A lymphocyte clone with a 45, XY karyotype with a 14/14 tandem translocation marker, the frequency of which is time-variable, has been observed in an ataxia telangiectasia patient. Cells with the marker chromotosome were not observed in fibroblasts cultures derived from a skin biopsy, nor was the marker observed in leukocyte cultures from the patient's two affected sibs.