MPK11-a fourth elicitor-responsive mitogen-activated protein kinase in Arabidopsis thaliana
MPK11-a fourth elicitor-responsive mitogen-activated protein kinase in Arabidopsis thaliana
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DOI：
10.4161/psb.21323
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发表时间：
2012-01-01
影响因子：
2.9
通讯作者：
Lee, Justin
中科院分区：
文献类型：
--
作者：
Eschen-Lippold, Lennart;Bethke, Gerit;Lee, Justin
病原体相关分子模式（PAMPs）识别病原体攻击或诱导导致防御信号，包括激活拟南芥中的三种促分裂原活化蛋白激酶（MPK），MPK 3，MPK 4和MPK 6。最近，我们证明了第四MPK，MPK 11，在用flg 22处理后的激活，flg 22是一种来自细菌鞭毛蛋白的22个氨基酸的PAMP。在这里，我们通过检查与其他两个PAMPs，elf 18（来自细菌延伸因子EF-Tu）和ch 8（来自真菌几丁质的N-乙酰壳八糖）的诱导扩展了研究。两种PAMP都导致MPK 11转录物的快速积累和MPK 11激酶活性的增加，表明多种PAMP（或应激）可以激活MPK 11。然而，可能由于功能冗余，细菌诱导的植物抗毒素积累并不绝对需要MPK 11。
Recognition of pathogen attack or elicitation with pathogen-associated molecular patterns (PAMPs) leads to defense signaling that includes activation of the three mitogen-activated protein kinases (MPKs), MPK3, MPK4 and MPK6 in Arabidopsis. Recently, we demonstrated the activation of a fourth MPK, MPK11, after treatment with flg22, a 22 amino acid PAMP derived from bacterial flagellin. Here, we extended the study by examining elicitation with two other PAMPs, elf18 (derived from bacterial elongation factor EF-Tu) and ch8 (N-acetylchitooctaose derived from fungal chitin). Both PAMPs led to rapid MPK11 transcript accumulation and increased MPK11 kinase activity, suggesting that multiple PAMPs (or stresses) can activate MPK11. However, probably due to functional redundancies, bacteria-induced phytoalexin accumulation does not absolutely require MPK11.