Correction of an unexpected increasing trend in glucose measurements during 7 years recruitment to a cohort study

Correction of an unexpected increasing trend in glucose measurements during 7 years recruitment to a cohort study
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DOI:
10.1016/j.clinbiochem.2011.08.1150
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发表时间:
2011-12-01
影响因子:
2.8
通讯作者:
Qvigstad, E.
Qvigstad, E.
中科院分区:
医学3区
文献类型:
--
作者:
Froslie, K. F.;Godang, K.;Qvigstad, E.

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目的:为了研究一个意想不到的,显着增加的血糖测量在7年的招募到cohort study.Design和方法:测量质量控制解决方案和孕妇血糖完成Accu-Chek传感器血糖仪。回归模型和控制charts.Results的时间趋势进行了分析:队列测量的趋势由加权线性回归的基础上独立的控制values.Conclusions:生物学上难以置信的数据趋势可以通过使用独立的控制值进行纠正。(C)2011年加拿大临床化学家协会。爱思唯尔公司出版All rights reserved.
Objectives: To study an unexpected, significant increase in glucose measurements during 7 year recruitment to a cohort study.Design and methods: Measurements of quality control solutions and blood glucose in pregnant women were done by Accu-Chek Sensor glucometer. Time-trends were analysed by regression models and control charts.Results: Cohort measurements were de-trended by weighted linear regressions based on independent control values.Conclusions: Biologically implausible trends in data can be corrected by using independent control values. (C) 2011 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.