Trends in prognostic factors and survival from cutaneous melanoma in Yorkshire, UK and New South Wales, Australia between 1993 and 2003
Trends in prognostic factors and survival from cutaneous melanoma in Yorkshire, UK and New South Wales, Australia between 1993 and 2003
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DOI：
10.1002/ijc.23495
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发表时间：
2008-08-15
影响因子：
6.4
通讯作者：
Forman, David
中科院分区：
文献类型：
--
作者：
Downing, Amy;Yu, Xue Qin;Forman, David
这项研究的目的是比较1993至2003年间两个潜在发病率截然不同的人群(英国约克郡和澳大利亚新南威尔士州)的预后因素和皮肤黑色素瘤存活率的趋势，并观察澳大利亚在黑色素瘤预防和早期发现方面的更大投资是否导致存活率的任何相对差异。从癌症登记数据库中识别出1993年至2003年在约克郡(n=4 170)和新南威尔士州(n=30,520)被诊断为侵袭性黑色素瘤的患者，并提取预后信息(年龄、性别、社会经济背景、肿瘤部位和布雷斯洛厚度)。计算年龄标化发病率、5年相对存活率和相对超额死亡风险。在1993-1995年和2001-2003年间，这两个地区的黑色素瘤发病率都有所上升。这些增加主要见于有厚度的肿瘤。
The aim of this study was to compare trends in prognostic factors and survival from cutaneous melanoma between 1993 and 2003 in 2 populations with dramatically different underlying incidence rates [Yorkshire, UK, and New South Wales (NSW), Australia] and to look at whether the greater investment in melanoma prevention and early detection in Australia has resulted in any relative differences in survival. Patients diagnosed with invasive melanoma between 1993 and 2003 in Yorkshire (n = 4,170) and NSW (it = 30,520) were identified from cancer registry databases and prognostic information (age, sex, socioeconomic background, tumour site and Breslow thickness) was extracted. Age-standardised incidence rates, 5-year relative survival and relative excess risk of death were calculated. Between 1993-1995 and 2001-2003, the incidence of melanoma increased in both areas. These increases were mainly seen in tumours with thickness