Clinical outcomes and cost-effectiveness of an externally applied electroceutical device in managing venous leg ulcers in clinical practice in the UK
Clinical outcomes and cost-effectiveness of an externally applied electroceutical device in managing venous leg ulcers in clinical practice in the UK
复制标题
DOI：
10.12968/jowc.2015.24.12.572
复制
发表时间：
2015-12-01
影响因子：
1.9
通讯作者：
Greaves, T.
中科院分区：
文献类型：
--
作者：
Guest, J. F.;Ayoub, N.;Greaves, T.
目的：从英国国家卫生服务（NHS）的角度，评估外敷电疗（EAE）装置加敷料和压缩包扎或继续其先前护理计划治疗下肢静脉溃疡（VLU）患者的成本效益。方法：对2013/14年度进行的EAE治疗进行前瞻性、单臂、非盲、临床和经济评估。患者的vlu接受6个有效单位的EAE治疗（每个单位2天），加上敷料和压迫包扎，为期12天。随后，对患者进行敷料和绷带联合治疗。每个患者都作为自己的对照，以便回顾性比较EAE治疗开始前12个月的临床结果、资源使用和与伤口相关的费用与治疗开始后的前12个月。EAE治疗的相对成本-效果是按2013/14年的价格估计的。结果：在开始EAE治疗的12个月内，77%的伤口愈合，23%的伤口改善。在EAE治疗前后12个月期间的有效性差异估计产生了12%的改善，健康收益为0.09 QALYs (p
Objective: To estimate the cost-effectiveness of treating patients with a venous leg ulcer (VLU) with an externally applied electroceutical (EAE) device, plus dressings and compression bandaging or continuing with their previous care plan, from the perspective of the National Health Service (NHS) in the UK.Method: This was a prospective, single-arm, non-blinded, clinical and economic evaluation of EAE therapy performed in 2013/14. Patients' VLUs were treated with six active units of EAE therapy (each unit for two days) plus dressings and compression bandaging over a period of 12 days. Afterwards, patients were managed with a combination of dressings and bandages. Each patient acted as their own control so that clinical outcomes, resource use and costs associated with the wound over 12 months before the start of EAE therapy were retrospectively compared with the first 12 months after the start of treatment. The relative cost-effectiveness of EAE therapy was estimated at 2013/14 prices.Results: Within 12 months of starting EAE therapy 77% of all wounds healed and the other 23% improved. This difference in effectiveness between the 12-months period before and after EAE therapy was estimated to yield a 12% improvement in health gain of 0.09 QALYs (p