Focal frontal (de)oxyhemoglobin responses during simple arithmetic
Focal frontal (de)oxyhemoglobin responses during simple arithmetic
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DOI：
10.1016/j.ijpsycho.2010.03.013
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发表时间：
2010-06-01
影响因子：
3
通讯作者：
Neuper, Christa
中科院分区：
文献类型：
--
作者：
Pfurtscheller, Gert;Bauernfeind, Guenther;Neuper, Christa
近红外光谱（NIRS）是一种功能性脑成像方法，能够研究皮质激活过程中的血流动力学变化。我们使用 52 通道 NIRS 系统研究了 10 名健康志愿者在简单心算过程中前额皮质的氧合血红蛋白和脱氧血红蛋白 ([oxy-Hb]、[deoxy-Hb]) 的变化。我们发现，十名受试者中有八名的背外侧前额叶皮质 (DLPFC) 中的 [oxy-Hb] 双侧相对增加，同时前额叶皮质 (APFC) 内侧区域减少。左侧 DLPFC 和 APFC 中的 [氧-Hb] 反应显着，而 [脱氧-Hb] 反应明显较小且不显着。这些观察结果是在“焦点激活/周围失活”的背景下讨论的。 (C) 2010 Elsevier B.V. 保留所有权利。
Near-infrared spectroscopy (NIRS) is a functional brain imaging method able to study hemodynamic changes during cortical activation. We studied the changes of oxy- and deoxyhemoglobin ([oxy-Hb],[deoxy-Hb]) with a 52-channel NIRS system during simple mental arithmetic in ten healthy volunteers over the prefrontal cortex. We found that eight of the ten subjects showed a relative focal bilateral increase of [oxy-Hb] in the dorsolateral prefrontal cortex (DLPFC) in parallel with a decrease in the medial area of the anterior prefrontal cortex (APFC). The [oxy-Hb] response in left DLPFC and APFC was significant, while the [deoxy-Hb] response was clearly smaller and not significant. These observations were discussed within the context of "focal activation/surround deactivation". (C) 2010 Elsevier B.V. All rights reserved.