Post-traumatic endophthalmitis caused by streptococcus species in preschool children: clinical features, antibiotic susceptibilities and outcomes.
Post-traumatic endophthalmitis caused by streptococcus species in preschool children: clinical features, antibiotic susceptibilities and outcomes.
复制标题
学龄前儿童链球菌引起的外伤后眼内炎：临床特征、抗生素敏感性和结果
DOI：
10.1038/s41433-021-01449-6
复制
发表时间：
2022-01
期刊：
影响因子：
--
通讯作者：
Lin X
中科院分区：
文献类型：
--
作者：
Yang Y;Sui W;Duan F;Li Y;Zeng J;Jiang Z;Liu M;Yuan Z;Lin X
背景/目的链球菌是儿童外伤后眼内炎的常见原因。本研究旨在分析学龄前儿童外伤性链球菌性眼内炎的临床特点、抗生素敏感性和转归。患者的平均年龄为3.3 ± 1.7岁，其中57.1%为男性。剪刀（28.6%，n = 6）是最常见的损伤原因; 86.7%的患者在家中受伤。I区（80.9%）是最常见的伤口部位; 90.5%的患者出现创伤性白内障。肺炎链球菌（47.6%）是最常见的分离株。草绿色链球菌占0-3岁儿童的58.3%，而S.肺炎占4-6岁儿童的66.7%。链球菌对头孢呋辛、左氧氟沙星和氧氟沙星的敏感率分别为100%、95.0%和90.5%。虽然所有患者均行玻璃体切割联合硅油填充术，但最终视力结果并不比数手指好。肺炎是最常见的病原体，不同年龄组的优势种不同。对常用抗生素头孢呋辛、氟喹诺酮敏感性较高。尽管及时治疗，学龄前儿童外伤后眼内炎的视力结果很差。
Background/ObjectivesStreptococcus is a common cause of post-traumatic endophthalmitis in children. This study aimed to analyse the clinical features, antibiotic susceptibilities and outcomes of traumatic endophthalmitis caused by streptococcus in preschool children.Subjects/MethodsPatients aged ≤6 years with traumatic streptococcal endophthalmitis seen at Zhongshan Ophthalmic Center between January 2013 and December 2018 were included in this retrospective study.ResultsIn total, 21 patients (21 eyes) were included. The mean age of the patients was 3.3 ± 1.7 years, where 57.1% were males. Scissors (28.6%,n= 6) were the most common cause of injury; 86.7% of patients were injured at home. Zone I (80.9%) was the most common wound site; 90.5% of patients presented with a traumatic cataract. In general,Streptococcus pneumoniae(47.6%) was the most common isolate. Viridans group streptococci accounted for 58.3% of cases in children aged 0–3 years, whileS. pneumoniaeaccounted for 66.7% of cases in children aged 4–6 years. The susceptibility rates of streptococcus to cefuroxime, levofloxacin and ofloxacin were 100%, 95.0% and 90.5%, respectively. Although all the patients underwent vitrectomy combined with silicone oil tamponade, the final visual outcomes were no better than counting fingers.ConclusionsAlthoughS. pneumoniaewas the most prevalent organism in general, the dominant species varied between different age groups. The commonly used antibiotics, cefuroxime and fluoroquinolone, showed higher antibiotic susceptibility. Despite prompt treatment, the visual outcomes of paediatric post-traumatic endophthalmitis in preschool children were poor.
登录
查看更多内容
影响因子：
3.6
作者：
Lee, Ching-Hsing;Lee, Lan;Yang, Meng-Ling
通讯作者：
Yang, Meng-Ling
DOI：
10.1097/iae.0b013e31820a67e4
发表时间：
2011-04-01
影响因子：
3.3
作者：
McCannel, Colin A.
通讯作者：
McCannel, Colin A.
影响因子：
2.2
作者：
Jacobs, David J.;Leng, Theodore;Gedde, Steven J.
通讯作者：
Gedde, Steven J.
影响因子：
4.2
作者：
Wykoff, Charles C.;Parrott, M. Brandon;Alfonso, Eduardo C.
通讯作者：
Alfonso, Eduardo C.
影响因子：
4.2
作者：
Kuriyan, Ajay E.;Weiss, Kathleen D.;Flynn, Harry W., Jr.;Smiddy, William E.;Berrocal, Audina M.;Albini, Thomas A.;Miller, Darlene
通讯作者：
Miller, Darlene