VASODILATOR RESPONSES FOLLOWING INTRACRANIAL STIMULATION OF THE TRIGEMINAL, FACIAL AND GLOSSOPHARYNGEAL NERVES IN THE CAT GINGIVA
VASODILATOR RESPONSES FOLLOWING INTRACRANIAL STIMULATION OF THE TRIGEMINAL, FACIAL AND GLOSSOPHARYNGEAL NERVES IN THE CAT GINGIVA
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DOI：
10.1016/0006-8993(91)91216-n
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发表时间：
1991-09-27
期刊：
影响因子：
2.9
通讯作者：
KARITA, K
中科院分区：
文献类型：
--
作者：
IZUMI, H;KARITA, K
研究了电刺激三叉神经、面部神经和舌咽神经对猫牙龈血流的影响。 对这些神经的颅内部分进行电刺激，并通过激光多普勒技术测量牙龈血流量。 对三叉神经、面部神经和舌咽神经的电刺激导致同侧牙龈血流量增加，无论是在颅神经完好的情况下还是在将其切割至髓质后。 刺激面部神经和舌咽神经的远端切口会引起血流量增加，但全身血压不会增加。 六甲铵预处理减少了面神经和舌咽神经电刺激引起的血流量增加，但对三叉神经刺激引起的血流量没有影响。 相比之下，用曲苯那明预处理减弱了三叉神经刺激的血流量增加，但不减弱面部和舌咽神经刺激引起的血流量增加。 阿托品、普萘洛尔和酚妥拉明对这些反应没有影响。 这些结果表明，自主神经系统，特别是副交感神经系统，负责面部和舌咽神经刺激引起的血流量增加，而三叉神经刺激的血流量增加是由三叉感觉神经的逆向血管舒张引起的。
The effects of electrical stimulation of the trigeminal, facial and glossopharyngeal nerves on gingival blood flow in the cat were studied. The intracranial part of these nerves was stimulated electrically, and gingival blood flow was measured by the laser Doppler technique. Electrical stimulation of the trigeminal, facial and glossopharyngeal nerves caused blood flow to increase in the ipsilateral gingiva both with the cranial nerve intact and after cutting it to the medulla. Stimulation of the distal cut ends of the facial and glossopharyngeal nerves elicited an increase in blood flow but no increase in systemic blood pressure. Pretreatment with hexamethonium reduced the increase in blood flow elicited by electrical stimulation of the facial and glossopharyngeal nerves, but had no effect on that elicited by stimulation of the trigeminal nerve. In contrast, pretreatment with tripelennamine attenuated the trigeminal nerve-stimulated blood flow increase, but not that elicited by stimulation of the facial and glossopharyngeal nerves. Atropine, propranolol and phentolamine had no effect on these responses. These results suggest that the autonomic nervous system, particularly the parasympathetic nervous system, is responsible for the blood flow increase elicited by facial and glossopharyngeal nerve stimulation, and that the trigeminal nerve-stimulated blood flow increase is induced by antidromic vasodilatation of the trigeminal sensory nerve.