Concentration and subcellular distribution of trace elements in liver of small cetaceans incidentally caught along the Brazilian coast
Concentration and subcellular distribution of trace elements in liver of small cetaceans incidentally caught along the Brazilian coast
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DOI：
10.1016/j.marpolbul.2004.03.009
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发表时间：
2004-10-01
影响因子：
5.8
通讯作者：
Readman, JW
中科院分区：
文献类型：
--
作者：
Kunito, T;Nakamura, S;Readman, JW
测定了河口海豚(Sotalia guianensis；n=20)、方斑海豚(Franciscana blainvillei；n=23)、大西洋斑海豚(Stenella Frontalis；n=2)、普通海豚(Stenella Frontalis；n=2)、普通海豚(Delphinus capensis；n=1)和条纹海豚(Stenella Blueoalba；n=1)肝脏中的微量元素(V、Cr、Mn、Fe、Co、Cu、Zn、Ga、As、Se、Rb、Sr、Mo、Ag、Cd、Sb、Cs、Ba、T-Hg、Org-Hg、Tl和Pb)的含量。N=1)1997年至1999年在巴西圣保罗州和巴拉那州海岸意外捕获。巴西鲸目动物肝脏中的微量元素浓度与北半球海洋哺乳动物文献中的数据相当。河口海豚和方氏海豚肝脏中V、Se、Mo、Cd、T-Hg和Org-Hg的含量均随年龄的增长而增加。铜的浓度非常高(范围为262-1970微克/克干重)和锌(范围为242-369杯/克干重)在河口海豚幼鱼的肝脏中观察到。河口海豚肝脏中V、Se、T-Hg、Org-Hg和Pb5种元素的含量显著高于河口海豚，而方氏海豚肝脏中的Mn、Co、As和Rb含量较高。海豚肝脏中有机汞/总汞的比值显著高于河口海豚，提示海豚肝脏中甲基汞的去甲基化能力可能低于河口海豚。部分海豚肝脏中的银含量较高(最高为20微克/克干重)，17%的海豚肝脏中银的含量高于汞。这些高Ag含量的样品也表现出较高的肝脏Se含量，这意味着肝脏中的Se可能对Ag有解毒作用。(Hg+0.5Ag)与Se之间的相关系数高于Hg与Se之间的相关系数，且Ag在肝细胞核和线粒体中的大量分布，也表明Se可能通过在海豚肝脏中形成Ag2Se来解毒。(C)2004爱思唯尔有限公司。保留所有权利。
Concentrations of trace elements (V, Cr, Mn, Fe, Co, Cu, Zn, Ga, As, Se, Rb, Sr, Mo, Ag, Cd, Sb, Cs, Ba, T-Hg, Org-Hg, Tl and Pb) were determined in liver samples of estuarine dolphin (Sotalia guianensis; n = 20), Franciscana dolphin (Pontoporia blainvillei; n = 23), Atlantic spotted dolphin (Stenella frontalis; n = 2), common dolphin (Delphinus capensis; n = 1) and striped dolphin (Stenella coeruleoalba; n = 1) incidentally caught along the coast of Sao Paulo State and Parana State, Brazil, from 1997 to 1999. The hepatic concentrations of trace elements in the Brazilian cetaceans were comparable to the data available in literature on marine mammals from Northern Hemisphere. Concentrations of V, Se, Mo, Cd, T-Hg and Org-Hg increased with increasing age in liver of both estuarine and Franciscana dolphins. Very high concentrations of Cu (range, 262-1970 mug/g dry wt.) and Zn (range, 242-369 mug/g dry wt.) were observed in liver of sucklings of estuarine dolphin. Hepatic concentrations of V, Se, T-Hg, Org-Hg and Pb were significantly higher in estuarine dolphin, whereas Franciscana dolphin showed higher concentrations of Mn, Co, As and Rb. Ratio of Org-Hg to T-Hg in liver was significantly higher in Franciscana dolphin than estuarine dolphin, suggesting that demethylation ability of methyl Hg might be lower in liver of Franciscana than estuarine dolphins. High hepatic concentrations of Ag were found in some specimens of Franciscana dolphin (maximum, 20 mug/g dry wt.), and 17% of Franciscana showed higher concentrations of Ag than Hg. These samples with high Ag concentration also exhibited elevated hepatic Se concentration, implying that Ag might be detoxified by Se in the liver. Higher correlation coefficient between (Hg + 0.5 Ag) and Se than between Hg and Se and the large distribution of Ag in non-soluble fraction in nuclear and mitochondrial fraction of the liver also suggests that Ag might be detoxified by Se via formation of Ag2Se in the liver of Franciscana dolphin. (C) 2004 Elsevier Ltd. All rights reserved.