Amino acid sequence homology between Piv, an essential protein in site-specific DNA inversion in Moraxella lacunata, and transposases of an unusual family of insertion elements.
Amino acid sequence homology between Piv, an essential protein in site-specific DNA inversion in Moraxella lacunata, and transposases of an unusual family of insertion elements.
复制标题
Piv（Moraxella lacunata 中位点特异性 DNA 倒转的必需蛋白）与异常插入元件家族的转座酶之间的氨基酸序列同源性。
DOI：
10.1128/jb.176.13.4160-4164.1994
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发表时间：
1994
影响因子：
3.2
通讯作者：
Glasgow,AC
中科院分区：
文献类型：
--
作者：
Lenich,AG;Glasgow,AC
对空泡莫拉氏菌DNA亚克隆倒置区的缺失分析表明，Piv是空泡莫拉氏菌编码的唯一因子，它是tfpQ/TFPI Pilin片段位点特异性倒置所必需的。预测的PIV氨基酸序列仅与一组插入序列元件的转座酶/整合酶有显著的同源性，提示PIV是一种新的位点特异性重组酶。
Deletion analysis of the subcloned DNA inversion region of Moraxella lacunata indicates that Piv is the only M. lacunata-encoded factor required for site-specific inversion of the tfpQ/tfpI pilin segment. The predicted amino acid sequence of Piv shows significant homology solely with the transposases/integrases of a family of insertion sequence elements, suggesting that Piv is a novel site-specific recombinase.