Induction of HSP-70 after hyperosmotic opening of the blood-brain barrier in the rat.
Induction of HSP-70 after hyperosmotic opening of the blood-brain barrier in the rat.
复制标题
大鼠血脑屏障高渗打开后 HSP-70 的诱导。
DOI：
10.1016/0304-3940(95)12208-7
复制
发表时间：
1995
影响因子：
2.5
通讯作者：
Noble,LJ
中科院分区：
文献类型：
--
作者：
Richmon,JD;Fukuda,K;Sharp,FR;Noble,LJ
The cellular response resulting from breakdown of the blood-brain barrier was evaluated 24 h after hyperosmotic infusion of mannitol into the internal carotid artery in the rat. Heat shock protein (HSP-70), a marker of cellular stress and/or injury, was induced in scattered patches of neurons and glia in regions of barrier breakdown. These findings suggest that osmotically induced breakdown of the blood-brain barrier may result in cell injury.
